Longer Lasting Caffeine

falser writes "Caffeine addicted geeks everywhere may rejoice that scientists have discovered a protein that appears to be responsible for amplifying the caffeine buzz. It also makes the effects last longer. Just one question: how soon until we have a new generation of ultra powerful caffeine products?"

Please Read the Article

[Mick D.]

The Chemical they are talking about (DARPP-32) is what makes as long lasting as it is in humans and mice. We already have it in our brains and it creates a positive feedback mechanism that keeps the stimulating effects of caffeine going.

The mice without DARPP-32 reacted very minimally to ~6 cups of coffee worth of caffeine.

Re:Why aren't there any caffiene patches?

[dreamchaser]

There are, you just can't buy them anywhere. Several hosptials are testing them as a means of helping people shake off the foggy after effects of anasthesia faster.

L-Tyrosine is known to do this

[Deagol]

A few years ago, I was researching the ACE "stack" (Asprin, Caffeine, and Ephedra). This is often used to either: a) loose weight; or b) increase effectiveness of strength training. L-Tyrosine is an amino acid which, when added to this mix (or caffeine alone), prolongs its effects and reduces the "jitters". So go visit your local health food store for similar stuff.

Never tried it myself, though.

Eat grapefruit.

[digitaltraveller]

Seriously. The naringin in grapefruit prevents the breakdown of xanthines in the liver. The net effect is that certain pharmacological substances last longer. It works with other drugs too. It can conceivably contribute to OD-type situations as well. Also, as someone above said, the amino acid tyrosine also will potentiate the effects, as will other substances. Bodybuilders use this for dieting and have known about this for years. They are after all mostly walking lab experiments [bodybuilders.com]