taatacgactc writes: "DARPA (DoD) is now supporting the development of a SPICE equivalent for biological circuits (aka BioSPICE). Best of all, it's to be "open source". Given the hyperexponential improvement in biological technology and the bioengineering efforts getting off the ground, fun stuff should be happening. Of course, there is the "dark side"." More information here. The submitter may be overstating the bit about "open source": the proposal says "All software developed as a part of the program will be open, in the sense that program performers and other DARPA authorized users will have the right to view, use, modify, and distribute code within the program authorized community. All derived works including revision, enhancement, modification, translation, abridgement and expansion of code will also remain open in this sense. ... The DARPA Director reserves the right to approve and exercise licensing arrangements depending on the context and the relevance to national security."