The oldest person living in Japan is 114 years old, reports the BBC. But "The number of people in Japan aged 100 or older has risen to a record high of nearly 100,000, its government has announced." Setting a new record for the 55th year in a row, the number of centenarians in Japan was 99,763 as of September, the health ministry said on Friday. Of that total, women accounted for an overwhelming 88%... Health minister Takamaro Fukoka congratulated the 87,784 female and 11,979 male centenarians on their longevity and expressed his "gratitude for their many years of contributions to the development of society"....

The higher life expectancy is mainly attributed to fewer deaths from heart disease and common forms of cancer, in particular breast and prostate cancer. Japan has low rates of obesity, a major contributing factor to both diseases, thanks to diets low in red meat and high in fish and vegetables. The obesity rate is particularly low for women, which could go some way to explaining why Japanese women have a much higher life expectancy than their male counterparts... But it's not just diet. Japanese people tend to stay active into later life, walking and using public transport more than elderly people in the US and Europe...

However, several studies have cast doubt on the validity of global centenarian numbers, suggesting data errors, unreliable public records and missing birth certificates may account for elevated figures. A government audit of family registries in Japan in 2010 uncovered more than 230,000 people listed as being aged 100 or older who were unaccounted for, some having in fact died decades previously. The miscounting was attributed to patchy record-keeping and suspicions that some families may have tried to hide the deaths of elderly relatives in order to claim their pensions.

Many coral reefs "have now turned ghostly white," reports CBS News — and "a major culprit is climate change."

SFGate adds that more than 50% of the world's coral reefs have been lost, mostly over the past 10 years, according to coral reef scientist Rebecca Albright at the California Academy of Sciences. "If changes aren't made soon, 90% to 99% of the coral reefs that are remaining could be deteriorated by 2050, Albright said..."

But CBS News notes that Albright's lab is the first in America to successfully spawn coral to regenerate the reefs: The lab is mastering the art and science of creating baby corals, and the scientists have brought their expertise into the wild. The location: the second-largest reef in the world, known as the Mesoamerican Reef, stretching some 700 miles along the coasts of Mexico, Belize, Guatemala, and Honduras... Armed with test tubes, the scientists quickly dove into the water and collected the tiny packets of gametes. Back on land, the eggs were fertilized, incubated, and then brought back into the wild. "Then we planted over 3,000 baby corals back to the reef," explained Albright. The baby corals are now two months old. The Roatan staff will dive in a few months to see how many survived.
Scientists are worried because bleaching events "are becoming more common," notes SFGate, "happening more frequently and affecting more parts of the world... The most current event was confirmed on April 15, 2024, and is still ongoing, impacting approximately 84% of the world's coral reefs as of August 31.

"It has been documented in at least 83 countries and territories."

One of the worlds in the TRAPPIST-1 system, a mere 40 light-years away, just might be clad in a life-supporting atmosphere," reports ScienceAlert.

"In exciting new JWST observations, the Earth-sized exoplanet TRAPPIST-1e shows hints of a gaseous envelope similar to our own, one that could facilitate liquid water on the surface." Although the detection is ambiguous and needs extensive follow-up to find out what the deal is, it's the closest astronomers have come yet in their quest to find a second Earth... [T]he first step is finding exoplanets that are the right distance from their host star, occupying a zone where water neither freezes under extreme cold nor evaporates under extreme heat. Announced in 2016, the discovery of the TRAPPIST-1 system was immediately exciting for this reason. The red dwarf star hosts seven exoplanets that have a rocky composition (as opposed to gas or ice giants), several of which are bang in the star's habitable, liquid water zone...

Red dwarf stars are also much more active than Sun-like stars, rampant with flare activity that, scientists have speculated, may have stripped any planetary atmospheres in the vicinity. Closer inspections of TRAPPIST-1d, one of the other worlds in the star's habitable zone, have turned up no trace of an atmosphere. But TRAPPIST-1e is a little more comfortably located, at a slightly greater distance from the star... [T]he spectrum is consistent with an atmosphere rich in molecular nitrogen, with trace amounts of carbon dioxide and methane.

This is pretty tantalizing. Earth's atmosphere is roughly 78 percent molecular nitrogen. If the results can be validated, TRAPPIST-1e might just be the most Earth-like exoplanet discovered to date. That is not a small if, though. Luckily, more JWST observations are in the pipeline, and the researchers should be able to validate or rule out an atmosphere very soon.
After analyzing four transits of TRAPPIST-1e across TRAPPIST-1, "We are seeing two possible explanations," says astrophysicist Ryan MacDonald of the University of St Andrews in the UK. "The most exciting possibility is that TRAPPIST-1e could have a so-called secondary atmosphere containing heavy gases like nitrogen. "But our initial observations cannot yet rule out a bare rock with no atmosphere..."

Astrophysicist Ana Glidden of MIT led the second team interpreting the results, and says "We are really still in the early stages of learning what kind of amazing science we can do with Webb. It's incredible to measure the details of starlight around Earth-sized planets 40 light-years away and learn what it might be like there, if life could be possible there."

"We're in a new age of exploration that's very exciting to be a part of."

After its six-year journey to Saturn's moon Titan, Dragonfly's rotorcraft lander "will fly like a large drone," explains its web page, spending three years sampling multiple landing sites to characterize Titan's habitability and look for "precursors of the origin of life." "However, the project has undergone multiple replans impacting cost and schedule, resulting in a life-cycle cost increase of nearly $1 billion and over 2 years of delays," according to an announcement from NASA's Inspector General.

From the Inspector General's report: The cost increase and schedule delay were largely the result of NASA directing [Johns Hopkins University] Applied Physics Laboratory to conduct four replans between June 2019 and July 2023 early in Dragonfly's development. Justifications for these replans included the COVID-19 pandemic, supply chain issues, changes to accommodate a heavy-lift launch vehicle, projected funding challenges, and inflation."
But its higher-than-expected life-cycle cost over $3 billion "will continue to absorb an increasing proportion of the Planetary Science Division's total budget," meaning Dragonfly's increased cost (and "additional budget constraints") have "contributed to a gap of at least 12 years in New Frontiers [planetary science] mission launches, and will jeopardize future priorities outlined in the National Academies of Sciences, Engineering, and Medicine's (National Academies) decadal surveys."

Yet a NASA press release notes the mission "has cleared several key design, development and testing milestones and remains on track toward launch in July 2028." Its software-defined radio has been completed, and the part of the spectrometer which analyzes Titan's chemical components for "potentially biologically relevant" compounds (as well as structural and thermal testing of the lander's insulation).

"The mission is scheduled to launch in July 2028 on a SpaceX Falcon Heavy launch vehicle from NASA's Kennedy Space Center in Florida."

Thanks to long-time Slashdot reader schwit1 for spotting this news on the space/science blog "Behind the Black".

Finland's second-largest university has announced new research suggesting that heart attacks could be an infectious disease.

[T]he research found that, in coronary artery disease, atherosclerotic plaques containing cholesterol may harbor a gelatinous, asymptomatic biofilm formed by bacteria over years or even decades. Dormant bacteria within the biofilm remain shielded from both the patient's immune system and antibiotics because they cannot penetrate the biofilm matrix.

A viral infection or another external trigger may activate the biofilm, leading to the proliferation of bacteria and an inflammatory response. The inflammation can cause a rupture in the fibrous cap of the plaque, resulting in thrombus [blood clot] formation and ultimately myocardial infarction... "Bacterial involvement in coronary artery disease has long been suspected, but direct and convincing evidence has been lacking," explains professor Pekka Karhunen [who led the study with researchers from the UK and Finland]. "Our study demonstrated the presence of genetic material — DNA — from several oral bacteria inside atherosclerotic plaques." The findings were validated by developing an antibody targeted at the discovered bacteria, which unexpectedly revealed biofilm structures in arterial tissue. Bacteria released from the biofilm were observed in cases of myocardial infarction. The body's immune system had responded to these bacteria, triggering inflammation which ruptured the cholesterol-laden plaque.

The observations pave the way for the development of novel diagnostic and therapeutic strategies for myocardial infarction. Furthermore, they advance the possibility of preventing coronary artery disease and myocardial infarction by vaccination.
"The research is part of an extensive EU-funded cardiovascular research project involving 11 countries..."

The Washington Post notes that past research "indicates that exercise helps some cancer survivors avoid recurrence of their disease."

But a new study "offers an explanation of how, showing that exercise changes the inner workings of our muscles and cells, although more study is still needed..." The study, published last month, involved 32 women who'd survived breast cancer. After a single session of interval training or weightlifting, their blood contained higher levels of certain molecules, and those factors helped put the brakes on laboratory-grown breast cancer cells. "Our work shows that exercise can directly influence cancer biology, suppressing tumor growth through powerful molecular signals," said Robert Newton, the deputy director of the Exercise Medicine Research Institute at Edith Cowan University in Perth, Australia, and senior author of the new study. His group's experiment adds to mounting evidence that exercise upends the risks of not only developing but also surviving cancer...

Scientists know contracting muscles release a slew of hormones and biochemicals, known as myokines, into our bloodstreams and have long suspected these myokines fight cancer. In some past studies with mice and healthy people, blood drawn after exercise and added to live cancer cells killed or suppressed the cancer's growth... [The new study tested cancer cells in high-tech petri dishes with blood drawn from cancer survivors.] Drenched in plasma from either the interval trainers or the lifters, many cancer cells quit growing. Quite a few died. (The blood drawn before exercise had no effects.) The cancer-fighting impacts were greatest with the blood drawn after interval training. Why? Additional testing showed this blood contained the highest concentrations of certain, beneficial myokines, especially IL-6, a protein that affects immune responses and inflammation...

What these results mean, Newton said, is that "exercise doesn't just improve fitness and well-being" in people who've had cancer. "It also orchestrates a complex biological response that includes direct anticancer signals from muscles..." Questions remain, of course. Can any type of exercise fight cancer? Newton and other researchers have doubts. The exercise in this study was strenuous, by design. "Earlier studies suggested that the stronger the exercise stimulus, the greater the release of anticancer myokines," Newton said... Even the weight training in this study was less potent than the intense intervals. But Newton believes weight training remains key to cancer fighting. "People with cancer who increase their muscle mass through resistance training also experience greater rises in circulating myokines," he said. More muscle means more myokines.

Surgeons in London report a surge in severe e-bike-related injuries, putting major strain on NHS trauma units. The BBC mentions a couple e-bike accidents overheard at the Royal London Hospital in Whitechapel. "A 32-year-old, fit and well student... a couple of days ago he fell off an e-bike sustaining a closed left tibial plateau fracture." Another case involved a little girl named Frida: "Six-year-old girl, she was hit by an electric bike, she has a closed tib/fib fracture." From the report: Surgeon Jaison Patel is seeing more and more cases like this. "It's a massive burden on our department and I'm sure it's the same across the whole of London," he tells us. "If we can reduce the number of patients coming in with these sorts of injuries it would be great for the patients obviously, but also takes massive pressure off us in the NHS."

Jaison deals with lower limb injuries. Just along the corridor his colleague Nick Aresti does the upper limbs. Nick explains that he is a cyclist himself, and it's something he encourages people to do for the benefit of their health. But, he has real concerns about e-bikes, and says: "What we've noticed with e-bikes is that the speed in which people are coming off is much higher and as a result, the injuries are much worse." He shows us X-rays of someone who has broken their collarbone. He explains that with e-bikes, the injuries they're seeing are much more severe, and as such, people are "struggling to get back to normality."

Nick and Jaison both agree it's something they're seeing increasingly more of as time goes by, and they think the industry needs better regulation. "We should do something about it, I don't think we can let this carry on," Jaison says. Over recent days of course, thousands of Londoners have taken to e-bikes to help beat the strikes. For many it has been an essential way to get about. Currently, anyone aged 14 or over can legally ride an e-bike. The power output of an e-bike's motor should be capped at 250 watts, and the motor should not be capable of propelling the bike any faster than 15.5mph (25kph), according to government rules.

London's Walking and Cycling Commissioner Will Norman says the rules need changing and says better regulation of the rentable electric bikes could be on the way. "We need to ensure that the vehicles are safe, that there's parking, they're not scattered all over the place, and that the batteries are safe," he says. "I'm really delighted that the government has now indicated in its English Devolution Bill that London and other cities across the UK will be getting more powers so again we can start regulating that, to ensure that they're safe for people to use and operate while they get around". The bill is currently going through parliament, and as yet there is no date for when it will be passed. Duncan Dollimore, head of campaigns at Cycling UK, who are members of the Electric Bike Alliance, argues against the regulation of e-bike usage. "The cost of inactivity-related health issues to the NHS each year is 7.4 billion pounds, and people cycling saves them 1 billion pounds. We have seen a slight rise in the number of incidents involving hired e-bikes in London, but the health benefits of people cycling outweigh the risks by around 20 to one."

Researchers in China have created synthetic magnetic fields within silicon photonic crystals, allowing them to steer and control light on a chip with unprecedented precision. "Beyond immediate applications, the work opens new avenues for studying quantum-inspired phenomena with light," reports Phys.org. "The ability to impose artificial gauge fields in photonic systems could enable devices for optical computing, quantum information, and advanced communication technologies." Slashdot reader alternative_right shares an excerpt from the report: The team achieved this by systematically altering the symmetry of tiny repeating units in silicon photonic crystals. Adjusting the degree of local asymmetry at each point allowed them to 'design' pseudomagnetic fields with tailored spatial patterns, without breaking fundamental time-reversal symmetry. Both theoretical analysis and experiments confirmed that these engineered fields can guide and manipulate light in versatile ways. To demonstrate practical applications, the researchers built two devices commonly used in integrated optics. One was a compact S-shaped waveguide bend that transmitted light with less than 1.83 decibels of signal loss. The other was a power splitter that divided light into two equal paths with low excess loss and minimal imbalance. In a final test, the devices successfully transmitted a high-speed data stream at 140 gigabits per second using a standard telecommunications modulation format, showing that the technique is compatible with existing optical communication systems. The research has been published in Advanced Photonics.

Physicists have confirmed Stephen Hawking's 1971 black hole area theorem with near-absolute certainty, thanks to gravitational waves from an exceptionally loud black hole collision detected by upgraded LIGO instruments. New Scientist reports: Hawking proposed his black hole area theorem in 1971, which states that when two black holes merge, the resulting black hole's event horizon -- the boundary beyond which not even light can escape the clutches of a black hole -- cannot have an area smaller than the sum of the two original black holes. The theorem echoes the second law of thermodynamics, which states that the entropy, or disorder within an object, never decreases.

Black hole mergers warp the fabric of the universe, producing tiny fluctuations in space-time known as gravitational waves, which cross the universe at the speed of light. Five gravitational wave observatories on Earth hunt for waves 10,000 times smaller than the nucleus of an atom. They include the two US-based detectors of the Laser Interferometer Gravitational-Wave Observatory (LIGO) plus the Virgo detector in Italy, KAGRA in Japan and GEO600 in Germany, operated by an international collaboration known as LIGO-Virgo-KAGRA (LVK).

The recent collision, named GW250114, was almost identical to the one that created the first gravitational waves ever observed in 2015. Both involved black holes with masses between 30 and 40 times the mass of our sun and took place about 1.3 billion light years away. This time, the upgraded LIGO detectors had three times the sensitivity they had in 2015, so they were able to capture waves emanating from the collision in unprecedented detail. This allowed researchers to verify Hawking's theorem by calculating that the area of the event horizon was indeed larger after the merger. The findings have been published in the journal Physical Review Letters.

Researchers in China have developed a "DNA cassette," a retro-styled plastic tape embedded with synthetic DNA strands that can store up to 36 petabytes of digital data -- enough to hold every song ever recorded. New Scientist reports: Xingyu Jiang at the Southern University of Science and Technology in Guangdong, China, and his colleagues created the cassette by printing synthetic DNA molecules on to a plastic tape. "We can design its sequence so that the order of the DNA bases (A, T, C, G) represents digital information, just like 0s and 1s in a computer," he says. This means it can store any type of digital file, whether text, image, audio or video.

One problem with previous DNA storage techniques is the difficulty in accessing data, so the team then overlaid a series of barcodes on the tape to assist with retrieval. "This process is like finding a book in the library," says Jiang. "We first need to find the shelf corresponding to the book, then find the book on the corresponding shelf."

The tape is also coated in what the researchers describe as "crystal armor" made of zeolitic imidazolate, which prevents the DNA bonds from breaking down. That means the cassette could store data for centuries without deteriorating. While a traditional cassette tape could boast around 12 songs on each side, 100 meters of the new DNA cassette tape can hold more than 3 billion pieces of music, at 10 megabytes a song. The total data storage capacity is 36 petabytes of data -- equivalent to 36,000 terabyte hard drives. The research has been published in the journal Science Advances.

An anonymous reader quotes a report from NBC News: Global warming in the United States is amping up the country's sweet tooth, a new study found. When the temperature rises, Americans -- especially those with less money and education -- drink lots more sugary beverages and a bit more frozen desserts. That amounts to more than 100 million pounds of added sugar (358 million kilograms) consumed in the nation a year, compared to 15 years earlier, according to a team of researchers in the U.S. and United Kingdom.

When temperatures go between 54 and 86 degrees (12 and 30 degrees Celsius), the amount of sugar the average American consumes goes up by about 0.4 grams per degree Fahrenheit (0.7 grams per degree Celsius) per day, based on researchers tracking of weather conditions and consumers' purchases. At 54 degrees, the amount of added sugar for the average American is a little more than 2 grams. At 86 degrees, it's more than 15 grams. Beyond that, appetites lessen and added sugar falls off, according to the study in Monday's Nature Climate Change.

"Climate change is shaping what you eat and how you eat and that might have a bad effect on your health," said study co-author Duo Chan, a climate scientist at the University of Southampton. "People tend to take in more sweetened beverages as the temperature is getting higher and higher," Chan said. "Obviously under a warming climate that would cause you to drink more or take in more sugar. And that is going to be a severe problem when it comes to health." The findings have been published in the journal Nature Climate Change.

President Trump on Tuesday issued a memorandum directing the FDA and HHS to crack down on misleading direct-to-consumer prescription drug ads, requiring clearer disclosure of risks and ensuring that promotions don't overstate benefits or push costly drugs over generics. Longtime Slashdot reader sinij shares an excerpt from the memorandum: The Secretary of Health and Human Services shall therefore take appropriate action to ensure transparency and accuracy in direct-to-consumer prescription drug advertising, including by increasing the amount of information regarding any risks associated with the use of any such prescription drug required to be provided in prescription drug advertisements, to the extent permitted by applicable law. The Commissioner of Food and Drugs shall take appropriate action to enforce the Federal Food, Drug, and Cosmetic Act's prescription drug advertising provisions, and otherwise ensure truthful and non-misleading information in direct-to-consumer prescription drug advertisements. "Advertising dollars is a major avenue for pharmaceutical companies to influence news and attempt to shape public opinion," comments sinij. "Advertising was a major contributor to painkiller addiction, where networks were hesitant to cover early reports of addictiveness. It is likely directly contributing today to lack of critical coverage of Ozempic. It is just too big of a conflict of interest to allow to stand."

NASA: After a year's worth of scientific scrutiny, the 'Sapphire Canyon' rock sample remains the mission's best candidate for containing signs of ancient microbial life processes. A sample collected by NASA's Perseverance Mars rover from an ancient dry riverbed in Jezero Crater could preserve evidence of ancient microbial life. Taken from a rock named "Cheyava Falls" last year, the sample, called "Sapphire Canyon," contains potential biosignatures, according to a paper published Wednesday in the journal Nature.

A potential biosignature is a substance or structure that might have a biological origin but requires more data or further study before a conclusion can be reached about the absence or presence of life. "This finding by Perseverance, launched under President Trump in his first term, is the closest we have ever come to discovering life on Mars. The identification of a potential biosignature on the Red Planet is a groundbreaking discovery, and one that will advance our understanding of Mars," said acting NASA Administrator Sean Duffy. "NASA's commitment to conducting Gold Standard Science will continue as we pursue our goal of putting American boots on Mars' rocky soil."

Researchers at the University of Tubingen have discovered that human brains process colors in remarkably similar ways across different individuals. The team used fMRI scans from 15 participants viewing various colors to train a machine-learning model that could then accurately predict which colors a second group was viewing based solely on their brain activity patterns.

Published in the Journal of Neuroscience, the study found that specific brain cells in the visual cortex consistently respond more strongly to particular colors across all participants. The discovery challenges long-standing philosophical questions about whether people perceive colors differently.

Dozens of polar scientists have warned that geoengineering schemes to manipulate the Arctic and Antarctic are dangerous, impractical, and risk distracting from the urgent need to cut fossil fuel emissions. The BBC reports: These polar "geoengineering" techniques aim to cool the planet in unconventional ways, such as artificially thickening sea-ice or releasing tiny, reflective particles into the atmosphere. They have gained attention as potential future tools to combat global warming, alongside cutting carbon emissions. But more than 40 researchers say they could bring "severe environmental damage" and urged countries to simply focus on reaching net zero, the only established way to limit global warming.

The scientists behind the new assessment, published in the journal Frontiers in Science, reviewed the evidence for five of the most widely discussed polar geoengineering ideas. All fail to meet basic criteria for their feasibility and potential environmental risks, they say. One such suggestion is releasing tiny, reflective particles called aerosols high into the atmosphere to cool the planet. This often attracts attention among online conspiracy theorists, who falsely claim that condensation trails in the sky -- water vapour created from aircraft jet engines -- is evidence of sinister large-scale geoengineering today. But many scientists have more legitimate concerns, including disruption to weather patterns around the world.

With those potential knock-on effects, that also raises the question of who decides to use it -- especially in the Arctic and Antarctic, where governance is not straightforward. If a country were to deploy geoengineering against the wishes of others, it could "increase geopolitical tensions in polar regions," according to Dr Valerie Masson-Delmotte, senior scientist at the Universite Paris Saclay in France. Another fear is that while some of the ideas may be theoretically possible, the enormous costs and time to scale-up mean they are extremely unlikely to make a difference, according to the review. [...]

A more fundamental concern is that these types of projects could create the illusion of an alternative to cutting humanity's emissions of planet-warming gases. "If they are promoted... then they are a distraction because to some people they will be a solution to the climate crisis that doesn't require decarbonising," said Prof Siegert. "Of course that would not be true and that's why we think they can be potentially damaging." Even supporters of geoengineering research agree that it is, at best, a supplement to net zero, not a substitution.