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Some Soft Drinks May Damage Your DNA

Posted by Zonk on Sun May 27, 2007 03:28 AM
from the argh-my-mitochondria dept.
Parallax Blue writes "The Independent is reporting new findings that indicate a common additive called sodium benzoate, found in soft drinks such as Fanta and Pepsi Max among others, has the ability to switch off vital parts of DNA in a cell's mitochondria. From the article: 'The mitochondria consumes the oxygen to give you energy and if you damage it — as happens in a number of diseased states — then the cell starts to malfunction very seriously. And there is a whole array of diseases that are now being tied to damage to this DNA — Parkinson's and quite a lot of neuro-degenerative diseases, but above all the whole process of aging.' European Union MPs are now calling for an urgent investigation in the wake of these alarming new findings."
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  • by pcmanjon (735165) on Sunday May 27 2007, @03:30AM (#19289829)
    "uropean Union MPs are now calling for an urgent investigation in the wake of these alarming new findings"

    While the FDA in the United States is doing what? Standing by turning their cheek?
    • by bl8n8r (649187) on Sunday May 27 2007, @05:50AM (#19290483)
      > While the FDA in the United States is doing what? Standing by turning their cheek?

      Since the FDA is a government body, they are bound by contract to
      do nothing until:

      a) A patent has been infringed
      b) Someone has violated the DMCA
      c) The RIAA finds out someone copied Sodium Benzoate to CD
        • by hazem (472289) on Sunday May 27 2007, @04:00AM (#19290005) Journal
          When I was in the army, I was in a unit where we didn't run as much as I was used to and I was gaining weight. So I started drinking diet sodas instead of regular sodas. About that time, I started getting horrendous headaches.

          One day in the chow hall, the TV showed an article from Duke University (nearby, I was in North Carolina) that covered Aspertame triggering migraines. So, I conducted my own little experiment. Some days I would drink normal fattening soda. No headaches. Then I would drink diet soda - and terrible headaches.

          I started noticing other things - if I got bad headeaches, I would track back to see what I ate/drank. Sometimes, it was something like a gum (so many have aspartame to be safe for the teeth).

          So for many years, I did what I could to avoid Aspartame. In the last 6 months, I took it a step further and have eliminated MSG and High Fructose Corn Syrup. I occasionally crave a soda but that's rare now. The cool part is that I FEEL so much better. Not just headaches, but now that fuzziness and "hot flash" feeling I'd get in the afternoons is gone.

          And I've eliminated all fast food except the local Burgerville. I can't stand to touch McDonalds, Taco Bell, or Wendy's now. When I've succumbed to a craving, I felt like crap.

          I either eat organic/natural, at local places that prepare such food, and my addiction of choice now is tea with a bit of organic sugar for sweetener.

          I might not live any longer for it, but I FEEL much better for the time I am alive.
          • by mr_matticus (928346) on Sunday May 27 2007, @09:09AM (#19291435)
            The reason why you feel like crap when eating something unusual is because you've allowed that consumption to lax and your body has adjusted to that diet. It does not follow that eating at Wendy's occasionally makes people ill. It makes YOU ill because your body is no longer accustomed to it.

            Along the same vein, vegetarians are encouraged to eat meat occasionally so that the enzymes that are intended to ingest it can remain in proper balance. If you're a vegetarian and never eat meat for years on end, but then one day you can't pass on that ham sandwich, it's going to hurt. That doesn't mean that people who eat meat are living a worse life.

            Likewise, if you grew up on a simple and narrow diet, say, for the sake of argument, something typical of a highland/steppe agrarian diet--grains and meat, and you suddenly ate spicy Indian food for a week, you'd probably have some digestive regrets.

            I'm not saying the opposite, either--eating fast food and sugar all the time is certainly not good for you. But if you make it a habit to eat a highly restricted diet, then breaking that diet will cause you pain. Eating an appropriate diet with moderation of all kinds of foods is no less healthy and far more fun. It's okay to eat at McDonald's sometimes if you like it. It's okay to order that six-chocolate pie on your birthday. It's okay to tear into that Haagen-Daaz when your week has gone to shit. It's habitual abuse of these foods that cause problems.
            • by hey! (33014) on Sunday May 27 2007, @08:50AM (#19291325) Homepage Journal
              An acquaintence of mine is a neuroscient. She won't touch Aspartame, because she says there are so many side effects, many of them neurological.

              In 1980, Aspartame failed to achieve FDA approval. However, this decision was reversed under a new, Reagan appointed commissioner it was approved. Subsequently it was the leading cause of FDA complaints for adverse reactions (in part this was due to its common use), until the FDA decided to stop counting them.

              It is probably true that most people are OK with it in modest quantities. But people should use it with caution and be on the lookout for complications.
  • nothing new (Score:5, Insightful)

    by wizardforce (1005805) on Sunday May 27 2007, @03:40AM (#19289897) Journal
    this is nothing new, sodium benzoate is used as a preservative in acidic foods and drinks and in the presence of citric acid it can evolve very small amounts of benzene. benzene is dangerous because it is what we call an intercalary mutagen- what that means is it can insert its self between the DNA helix grooves and that is what can mess up DNA copying and transcription [translation from DNA to RNA to proteins etc.] in the USA benzene is allowed at 10ppb but in soem states it can be lower [california is 5ppb] to give an idea of how much that is an olympic swimming pool is 25,000 gallons, 95,000 liters and so 10ppb would be about a gram of benzene taken by weight. soft drinks in other countries have been reported to have up to 85 ppb although this can be fixed by reducing the amount of sodium benzoate and or citric acid in combination. citric acid can be replaced by malic acid which imparts that sour flavor in drinks.
  • Frogurt (Score:5, Funny)

    by lamasquerade (172547) on Sunday May 27 2007, @03:52AM (#19289957)
    Shopkeeper: Take this object, but beware it carries a terrible curse!
    Homer: Ooh, that's bad.
    Shopkeeper: But it comes with a free frogurt!
    Homer: That's good.
    Shopkeeper: The frogurt is also cursed.
    Homer: That's bad.
    Shopkeeper: But you get your choice of toppings.
    Homer: That's good!
    Shopkeeper: The toppings contain potassium benzoate.
    [Homer looks puzzled]
    Shopkeeper: ...That's bad.
    Homer: Can I go now? ....and just to add some actual comment: with the constant uncovering of bad effects of things thought previously to be entirely safe I find myself beginning to side with the anti-GM people... I mean I don't think it's definitely harmful, but the positive effects are mainly economic (and so reletively uninteresting unless money turns you on)- why can't be just deal with the good old food we're used to and know isn't going to do anything bizarre to our bodies. Not just with GM but with over-processing of any kind. When you've got beverages being made in ways to minimise only cost and maximise only the positive reaction with our taste buds then you're going to get stuff like this.
    • Re:Frogurt (Score:5, Insightful)

      by wizardforce (1005805) on Sunday May 27 2007, @04:10AM (#19290057) Journal

      but the positive effects are mainly economic

      we have been genetically modifying foods in one way or another for hundreds of years- only now are we using genes from OTHER species. crops engineered to be resistant to a certain pest can reduce the amount of pesticide or [ergot fungus] that gets into the food supply. there are genes that over time have broken or exist in similar but uncrossable species that are very useful. in the case of yellow rice for example, a gene for beta carotene was introduced resulting in a rice that can help prevent blindness in third world countries where rice is a major food crop. the gene that produces vitamin C in mammals is broken in primates and other species that if corrected could prevent scurvy in malnourished nations. it is good to test and try to understand the effects of genetic engineering but to blindly fear it because of things like this is irresponsible
      • by saforrest (184929) on Sunday May 27 2007, @06:21AM (#19290639) Homepage Journal
        the gene that produces vitamin C in mammals is broken in primates and other species that if corrected could prevent scurvy in malnourished nations. it is good to test and try to understand the effects of genetic engineering but to blindly fear it because of things like this is irresponsible

        You're not just talking about genetically engineering foods, but now humans? On a massive, global scale?

        1) Vitamin C is an essential nutrient for higher primates for a reason: our ancestors ate a lot of it, and thus no longer needed to produce it. These genes for synthesizing it that you want to "reactivate" haven't been expressed for millions of years, which means they haven't been selected on (to the same degree). For a programming analogy, how quickly does commented-out code become obsolete?

        It's not at all clear that we're still capable of synthesizing Vitamin-C, that it's just a matter of "turning on" a gene somewhere: it might require extensive implantation of non-primate mammalian DNA into our genomes. And this is not a small change.

        2) Who would research and administer this genetic re-engineering system? Big Pharmaceutical, that's who. You're naive if you think there's any good side to letting go about re-engineering the genes of any person, let alone impoverished people who are in less of a position to speak up about abuses.

        3) I frequently hear pitches like this, for certain types of technological solutions which could save the lives of the desperate poor. In addition to your suggestion, we could, for example:
          - i) genetically engineer a number of crops with higher yields, providing more food,
          - ii) blanket Africa with DDT, killing mosquitoes (and therefore preventing malaria transmission),
          - iii) actively destroy swampland in rural Africa and other tropical regions, to reduce the size of mosquito breeding grounds.
        The argument for these technologies (saved human lives) is easy to advance. There are various specific counterarguments to be used for specific cases, but there are two general counterarguments:

        A straightforward swap of human lives in exchange for some consequence we haven't defined or investigated is never a great idea. What if we replace all crops with engineered ones, but those are all wiped out ten years later by a plague that preys on the new genetic homogenity of these crops? What if there's something else that grows in swamps that, it turns out, we really need? The appeal to lives saved is always an emotional appeal, but there's no point to the trade if we don't know the price.

        The reasons for Third World poverty are not technological, but social and political. We could give more food to hungry people now; we don't need to wait till we get higher-yield crops. (To relate to your example, we could send Vitamin-C pills to malnurished nations now: surely this would be cheaper that a widespread program of genetic re-engineering!) And if we aren't giving it away now, aren't we fooling ourselves by thinking that we will when we have more to give away?
      • Re:Frogurt (Score:5, Interesting)

        by Snaller (147050) on Sunday May 27 2007, @08:43AM (#19291287) Journal
        "The fact is, we're living longer and healthier with all of this "processed crap" than we ever did with "good old food". "

        Actually no, that's not a fact - remember there is "life lag", the numbers we look at are always 60-70 years behind. The people who die now eat their stuff a long time ago. And many scientists are thinking the curve will drop drastically in the future because of the crap people eat now - the obesity-related diseases in the west have exploded with a ton of related ilnesses.

        "This is what gets me about GMO opponents - they fail to understand that there is a significant proportion of the world that would kill for ANY semblence of nutrition."

        And why is that? Because the rich west don't give a shit about them. When you get right down to it, most people don't care about the next guy - let him die. Which is also why its dangerous chemically added stuff, who cares if you bump off some people - as long as there are enough left to buy it!
        • Re:Frogurt (Score:5, Informative)

          by hankwang (413283) * on Sunday May 27 2007, @07:18AM (#19290857) Homepage

          life expectancy at birth has gone from about 50 years [...] You think that 25 used to literally be "mid life". Half your life was likely over by 25.

          Life expectancy at birth includes child diseases that killed about 20% of the children before the age of 5. See page 6, fig 3 of the US life tables. [cdc.gov] Once you survived the first few years of your life, your life expectancy would increase considerably. See page 30 of the report: at the age of 25, your life expectancy was 65. Your midlife would be around the age of 34. Nowadays, the life expectancy only increases from 77.5 to 78.5 years between the age of 0 and 25 years.

  • Beer is still safe.
  • by cruachan (113813) on Sunday May 27 2007, @04:07AM (#19290043)
    Not to say that there might not be an issue, but The Independent was the Newspaper that first ran the WiFi scare in the UK - a couple of weeks ago and well before the BBC - and last Sunday's scare in the paper was over baby alarms. Both pieces were examples of really bad science journalism with widespread scattering of the term 'radiation' throughout and cleverly writen to wrap as much scaremongering as possible up in pseudo-objective and precautionary language.

    Today's leader article is a classic 'For The Sake Of The Children' rant (http://comment.independent.co.uk/leading_articles /article2586569.ece)
  • by Greg_D (138979) on Sunday May 27 2007, @04:46AM (#19290213)
    ... to Coca Cola. That was after growing up for 21 years in which cola was a treat that almost never found its way into my family's household.

    Sugar? Check.
    Caffeine? Check.
    Citrus flavor? Check.

    But the main thing that I loved above all else was the bite from the fizz. After I realized this, I made a quick switch to seltzer water with a lemon or lime wedge and sometimes some crushed mint. I get the same bite, but without all that extra stuff.

    Dropped 30lbs in 3 months after that switch.
  • No kidding. (Score:5, Insightful)

    by zCyl (14362) on Sunday May 27 2007, @04:58AM (#19290271)
    Not to mention sodium benzoate causes headaches in a good percentage of humans, and over the long term has been found to trigger obesity and diabetes in lab rats. (It might do this in humans too over the long term, but it's hard to get humans to sign up for such studies.)

    It would be funny if it weren't so sad that people drink diet sodas that are loaded with this, and they think they are doing their body a favor.
  • Coca-Cola Zero (Score:5, Informative)

    by dysfunct (940221) * on Sunday May 27 2007, @06:37AM (#19290719)
    If anybody's interested: There's currently quite a number of marketing campaigns across of Europe for the new Coca-Cola Zero. According to its Wikipedia's entry [wikipedia.org], the product can contain sodium benzoate depending on the country where it's sold. If you're cautious and want to be on the safe side, you might want to stick to regular Coca Cola or Diet Coke which appear not to contain this stuff.
    • A no win situation (Score:5, Insightful)

      by rolfwind (528248) on Sunday May 27 2007, @03:54AM (#19289969)
      Soda rots your teeth and probably contributes to diabetes II.

      Diet Soda, it has been found in a European study (German?) to fuck with your blood sugar level - the body thinks it's getting sugar, pumps you with insulin, and it turns out you aren't getting any.

      And all the sugar-substitue additives have been questions for years.

      Drink Water or at worst carbonated water. Maybe a little tea or iced tea made from decent leaves (not the garbage leaves in lipton surrounded by bleached paper to dunk in water), or even a little expresso.

      Leave out the soda pop, leave out most of the milk (thought to contribute to kidney stones), leave out the juice, etcetera. And for god's sake leave out anything sweetened with high fructose corn syrup - poison. Our ancestors were able to make due with water as a drink and so our bodies should be acclimated to it.

      The funny thing is, we have access to the cleanest water in history, without it being muddy or full of minerals, and we found a "need" to have all this oversweetened garbage instead.

      It's not hard, start drinking for a week - you'll be over the sweet addiction. I like ice water the best. If you have to, treat yourself to a juice drink or milk once a day.
      • by nietsch (112711) on Sunday May 27 2007, @05:38AM (#19290445) Homepage Journal
        "Our ancestors were able to make due with water as a drink and so our bodies should be acclimated to it."
        Sorry, but do you have any proof for this except from "it should be, because out ancestors did it"? You may disguise it with some evolutionary selection handwaving, but basically you are propagating the romantic notion of 'le bon sauvage' (the good wild [man]). Did you ever compare the average lifespan of 'our ancestors' with the current average lifespan? Maybe current culture does some things detrimental to your health, but overall it is much better then what our ancestors had to go through if you measure it by lifespan.
        The other hidden argument that you use is that it is morally better to restrict yourself and almost never indulge on luxury. What are you, some monk that derives pleasure (oh no, bad!) from chastising himself?
        The article was about someone making a health scare over an additive that has been tested and approved decades ago, on the basis of some muddy test in-vitro by, afaict, one researcher. Where are the references to peer-reviewed journals, have others replicated his results, etc. People apparently have a hard time understanding that a poison is not only in the substance, but also in the dose. It could very well be that with normal consumption you never reach a significant dose that has any effect at all.
        I think that there is more danger in the trip to the grocery store wit your car, than there is in the additives in the soda pop you buy there.
    • No publication? (Score:5, Insightful)

      by jenik (1030872) on Sunday May 27 2007, @06:14AM (#19290609)
      PubMed doesn't seem to have any papers on this, at least by this Piper guy... I'll wait for a peer reviewed publication.
    • by Kierthos (225954) on Sunday May 27 2007, @08:47AM (#19291315) Homepage
      Okay, here's some numbers for you...

      The acceptable FDA levels for caffiene consumption is 200 mg/day. (please note the lack of any determination of this based on how much you weigh.)

      The acceptable FDA levels for aspartame consumption is 50 mg/kg of body weight. The more you weigh, the more you can acceptably consume. (The American Diabetic Association disagrees, and puts the acceptable levels at 17 mg/kg of body weight.)

      The acceptable FDA levels for sodium benzoate consumption is 340 mg/day. Again, note the lack of any change in this based on your body weight.

      Now, sodium benzoate is what the article is about, right? So, how much sodium benzoate is in a soda?

      All of these are for 12 oz. cans.

      Pepsi: 1.15 mg
      Mountain Dew: 2.3 mg
      Diet Mountain Dew: 2.5 mg
      Dr Pepper: 1.15 mg
      Coke: 1.15 mg
      Diet Coke: 2.5 mg

      So, if you're a Dr Pepper "junkie" like me, you'd have to drink almost 300 cans a day before you would have to worry about being above the FDA guidelines.

      Now, yes, of course, it's possible that the FDA data is out of date. Yes, it's possible that there hasn't been enough study and maybe the acceptable levels of sodium benzoate need to be adjusted.

      Even if they're off by a factor of 10, how many people do you know that drink 30 Pepsis a day?

      More research, less scare tactics. Thank you.