Stories
Slash Boxes
Comments

News for nerds, stuff that matters

Slashdot Log In

Log In

Create Account  |  Retrieve Password

The Cure for Cancer Might be: HIV

Posted by Hemos on Mon Feb 14, 2005 12:25 PM
from the probably-not dept.
RGautier writes "Wired News has published that Scientists have successfully modified the AIDS-causing HIV in such a way that it can attack metasticized melanoma (cancer cells). The impact of genetic research on cancer research is in and of itself amazing. To mix this with the strategy of using one strong enemy against another is brilliance! Research will continue, obviously, but they are already reporting success on living creatures." Just think: between HIV and carrots we'll be all set.
+ -
story
This discussion has been archived. No new comments can be posted.
The Fine Print: The following comments are owned by whoever posted them. We are not responsible for them in any way.
 Full
 Abbreviated
 Hidden
More
Loading... please wait.
  • by beatdown (788583) * on Monday February 14 2005, @12:26PM (#11668989)
    The bad news is you have cancer. The good news is you have HIV!
  • by geoffspear (692508) * on Monday February 14 2005, @12:26PM (#11668992) Homepage
    If you're gotten rid of 80% of the virus, you might not want to market it as "derived from HIV". Really.
    • by EaterOfDog (759681) on Monday February 14 2005, @12:32PM (#11669065)
      Maybe HIV-Lite? Or I Can't Believe It's Not HIV!
    • by Anonymous Coward on Monday February 14 2005, @12:36PM (#11669129)
      I don't really think it would make sense to downplay any involvement with HIV. Lets say they decide to call it something else and at a later point in time it's "revealed" that people are being strategically infected with HIV... even in a reduced state... don't you think people would be outraged that this information was withheld? I think the natural reaction from most of the public (through ignorance, of course) would be "why would they keep it from us... is there something they didn't want us to know?"

      Best to be as open as possible right from the start to avoid any misconceptions. (Or media backlash.)
  • I think I'd go with the carrots. I dunno, maybe I'm just weird.
  • by gbitten (306952) on Monday February 14 2005, @12:29PM (#11669025)
    The microscopic version of Alien Vs. Predator
  • by Faust7 (314817) on Monday February 14 2005, @12:29PM (#11669032) Homepage
    "I prescribe disease-riddled hookers. Take one after every meal."
  • by kiwidefunkt (855968) on Monday February 14 2005, @12:29PM (#11669035) Homepage
    So when this hits the market, will HIV be cheaper in Canada than the US?
  • by your_mother_sews_soc (528221) on Monday February 14 2005, @12:30PM (#11669039)
    I knew this girl in college that did amazing things with candles and vegetables, including carrots. I know for a fact she won't die of cancer. She OD'd in '86.
  • Nothing new really (Score:5, Informative)

    by FiReaNGeL (312636) <fireang3l@hotmail. c o m> on Monday February 14 2005, @12:35PM (#11669117) Homepage
    Gene therapy use lentivirus-based (HIV) vectors for quite some time now; it's nothing new really; a marketing team found the 'Cure Cancer with HIV!' twist interesting I guess.

    When pseudotyped with the right envelope, these virus can infect efficiently any type of cell. They can also transduce non-dividing cells, which is usefull. They lack almost every gene of HIV; they retain certain structures which allow packaging of the genome in the virus and the viral promoter, but that's about it. Viruses are packaged in special cell lines containing the viral components on plasmids most of the time, and preparations are tested for recombinants. Its the best technology out there, but its nothing new, really.
  • Brilliance? (Score:5, Informative)

    by aprilsound (412645) on Monday February 14 2005, @12:40PM (#11669169) Homepage
    To mix this with the strategy of using one strong enemy against another is brilliance!
    As others have said, it sounds potentialy dangerous (mutation et al), but the idea of using something bad to treat something else bad is by no means innovative. A few examples:

    chemotherapy - is just poison. it works because the cancer cells absorb the poison much quicker than normal cells.

    radiation therapy - again, radiation by itself is bad.

    most over the counter acne treatments - are just some form or acid that kills the bacteria on the skin
    As for reengineering a virus to take on something else, while facinating, its hardly a new idea. If you are interested in this sort of thing and haven't read Orson Scott Card's Xenocide [amazon.com] (part of the Ender Series), you might check it out.

  • Mis-titled article (Score:5, Informative)

    by rpdillon (715137) on Monday February 14 2005, @12:41PM (#11669185) Homepage
    I'm not too much in the know about bio-tech, but it seems that this HIV-transport-for-another-virus doesn't actually attack the cancer:

    The researchers programmed the altered virus package to attack a protein on the cancer cell surface called p-glycoprotein, which causes problems in cancer patients by shuttling cancer drugs away from the cell. In other words, p-glycoprotein causes resistance to cancer medication. Scientists could customize the system to target any protein on the surface of a cell, Chen said. He and his colleagues have seen success with about a dozen different molecules, including brain and other blood cells, he said.

    Except for the last sentence, it makes it seem as though this is only a way to pave the way for more conventional treatments. The last sentence doesn't make sense to me, given the context. I can understand how the proteins on the surface of a cell could qualify as "molecules", but then the structure of the sentence makes it seem like they're calling brain and blood cells molecules:

    He and his colleagues have seen success with about a dozen different molecules, including brain and other blood cells, he said.

    I'm still waiting for a virus that attacks the actual cancer cells. I remember hearing something about it a while back, but then it seemed to die off. Anyone been following it?

  • by wowbagger (69688) on Monday February 14 2005, @12:44PM (#11669225) Homepage Journal
    The summary of the article (and many of the comments) would have you believe this is a potential "cure for cancer".

    Melanoma is a subset of the set of all cancers - specifically, it is a form of skin cancer - more specifically, it is a cancer formed from the skin cells that give skin its pigmentation.

    Melanoma is NOT *all cancers* - thus even if this modified virus will kill 100% of all melanomas and have 0% harmful side-effects this does NOT make it a "cure for cancer" - merely a "cure for a type of cancer".

    The will need to generalize this virus to attack ALL cancerous cells, and NOT to attack any other cells.

    Now, if you can work out how a virus can tell the difference between a cancerous cell and a normal but rapidly reproducing cell, you have a Nobel prize awaiting.
    • Re:battlefield (Score:5, Insightful)

      by Ironsides (739422) on Monday February 14 2005, @12:29PM (#11669030) Homepage Journal
      You assume it isn't already. Remember what White Bloodcells do? Along with anti-biotics and vacines? All this is doing is adding in another weapon to the arsenal.
    • by Quasar1999 (520073) on Monday February 14 2005, @12:33PM (#11669086) Journal
      Do we really want to turn our bodies into a battlefield for germ warfare?

      I ask myself that same question everytime I eat out... the answer is yes... yes I do... taco-hell is just too good to pass up, and the other germs I picked up from KFC and the chinese food place down the street will battle it out... ;)
    • Re:battlefield (Score:5, Insightful)

      by imag0 (605684) on Monday February 14 2005, @12:34PM (#11669097) Homepage
      Do we really want to turn our bodies into a battlefield for germ warfare?

      Yes. You better believe it.

      After seeing my mother die from cancer I would give anything to make sure no one else would ever have to go through what me and my sister did.

      In short, hell yeah. Bring it on.