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Scientists Grow New Eyes (In Tadpoles)

Posted by timothy on Thu Nov 20, 2008 04:16 PM
from the good-place-to-start dept.
MagnetDroid writes "Michael Zuber and his colleagues from SUNY Upstate Medical University have shown how to regrow frogs eyes using stem cells. Zuber's team genetically engineered the stem cells to express transcription factors that regulate eye development and, when they transplanted them into frog embryos that had had one eye removed, they regrew into fully functioning tadpole eyes. Unfortunately, the same trick doesn't work in mammals but Zuber hopes to find chemicals that activate the transcription factors without genetic engineering and says this might one day lead to new treatments for diseases linked to cell loss in the retina."
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  • "If you could only see what I have seen with your eyes..."
  • ...Apple releases "Pod" and "Phone".

  • Hmm...Looks like they couldn't be botherd to implant the new eye in alignment with the other. I wonder how it looks once the tadpole is fully developed.

    Also, I wonder how long until scientists manage to reproduce the regressive gene for necks and pointy collars [wordpress.com].
  • "Do you see what I see?"
      Said the science experiment to his fellow frog.
    "Do you hear what I hear?" ...

  • I'd much rather have artificial eye-implants. Kind of like Geordi LaForge.
    • Really? I mean, being able to see into other parts of the ultraviolet spectrum could be kind of neat, you really want your vision to be so easily taken away? Steal your VISOR [memory-alpha.org] and all of a sudden you're absolutely blind.

      I could see wanting to go for the ocular implants [memory-alpha.org] that Geordi got later on though. Those I suppose could still be stolen, but far less easily than a VISOR(and no more susceptible to theft than organic eyes). Plus they're more powerful.
      huh, apparently Seven of Nine got something like these

      • Seven had one of her eyes removed as a child, when she was originally assimilated. The Voyager doctor gave her a replacement implant. I don't think that it (normally) did anything more than normal human sight...although there were a few episodes that they "tuned" it to act as an extra-dimensional detector or something.
      • you really want your vision to be so easily taken away?

        What's the difference with real eyes? Give me a spoon, a fork or any combination thereof and I can make you blind in a few seconds.

        Personally, I'd just like some extra eyes. Full 360 degrees vision seems cool, and I can also figure out some uses for eyes on my toes. (I just hope skirts won't go out of fashion).

        PS: xkcd reference intended.

  • Instead of wasting money on growing eyes they should be figuring out how to make a
    pesticide-resistant frog that can survive the f&^#ing chemical soup we humans subject them to.
    Read up, kids:
    http://www.eurekalert.org/pub_releases/2008-11/uop-prf111108.php [eurekalert.org]

    • Re: (Score:2, Funny)

      by Anonymous Coward

      If given the chance a frog would kill you and your whole family. Now is not the time to go soft on frogs.

      • Re: (Score:1, Funny)

        by Anonymous Coward

        yea, and it's only 99% mortality... you know what the opposite of mortality is right? immortality. 1% of frogs are fucking immortal now. mother fucker, we're ganna have a crisis on our hands here soon.

    • Instead of wasting money on growing eyes they should be figuring out how to make a
      pesticide-resistant frog that can survive the f&^#ing chemical soup we humans subject them to.

      But pesticide-resistant frogs may end up quite incapable of eating mosquitoes. Just ask the Haggunenons.

    • 'Instead of wasting money on growing eyes ...'

      French scientists work on growing legs.

  • My eyes! (Score:3, Funny)

    by 427_ci_505 (1009677) on Thursday November 20 2008, @04:43PM (#25838111)

    What has been seen, cannot been unseen.

    • This isn't about helping frogs. Its about regrowing lost tissue for humans. They start with frogs because the are better at regenerating lost tissue than mammals. Step two will most likely be to attempt this with adult amphibians, then move on to embryonic mammals. This is more of a proof of concept than a revelational advance in scince. We're still many decades away from a stem cell rich paste you stuff into your disgusting empty eye socket.
    • Well, they cut the eye off of the tadpole, it seems only polite to regrow it for them. Geez, the manners of young anonymous cowards these days...

  • by Polo (30659) * on Thursday November 20 2008, @05:52PM (#25839093) Homepage

    Does this make anyone think of the 20-eyed frog from the polluted lake in The Simpson's Movie?

  • Screw eyes, grow me some new damm teef! Sharks do it all the time, even WITH laser beams surgically implanted into their skulls.