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Brains Work Best At Age of 39

Posted by ScuttleMonkey on Mon Oct 27, 2008 12:39 PM
from the sounds-like-a-good-last-day-to-me dept.
Scientists at the University of California Los Angeles are reporting that while some people may think "life begins at 40," all it seems to do is slow down. According to recent research, at age 39 our brain reaches its peak speed, and it's all downhill after that. "The loss of a fatty skin that coats the nerve cells, called neurons, during middle age causes the slowdown, experts say. The coating acts as insulation, similar to the plastic covering on an electrical cable, and allows for fast bursts of signals around the body and brain. When the sheath deteriorates, signals passing along the neurons in the brain slow down. This means reaction times in the body are slower too."
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  • by Farmer Tim (530755) <roundfile.mindless@com> on Monday October 27 2008, @12:40PM (#25530255) Journal

    I'm getting old...

    • Fraud Alert: The results are wildly over-interpreted. The conclusions are guessing, not science.

      Maybe older people don't take finger-tapping seriously. Maybe younger people are far more likely to have played computer games.

      I met a man who was 55 who told me that he didn't get a good score on a computer pinball game he had just begun playing because he was old. Two weeks later, when I saw him again, he said his score had tripled.

      Quote from the article linked by Slashdot: "Significantly, the research suggests that the myelin breakdown process should also reduce all other brain functions for which performance speed is dependent on higher AP frequencies, including memory; ..."

      That's wild over-interpretation. There is no "should" in science. There is only theory, and it is necessary to emphasize that theories are only that, theories.
      • So in a nutshell you're saying I'm not too old and slow to get a first post.

      • Maybe so, but I'm still planning on increasing my intake of bacon, fried chicken and greasy burgers, you know, just in case.
      • I think that the word you seek with regard to their interpretation of the results is "hypothesis". Were it a Theory, then a claim of over-interpretation would need citation.

        This is besides the fact that the "word" over-interpretation doesn't make sense. Try "wild speculation" or "gross misinterpretation" next time.

        As to the There is no "should" in science thing: try learning about science one day. Any scientific hypothesis must be able to make certain predictions. Predictions are worded in the subjunctive or conditional, depending on the subject matter and placement of the word. The use of the word "should" in relation to science is quite appropriate for the purposes of prediction.

  • by bloodninja (1291306) on Monday October 27 2008, @12:43PM (#25530301)

    ...at age 18.

    I can't wait for the spam that will advertise me an 18 year old dick, a 39 year old brain, and a 65 year old bank account.

  • Interestingly, AFAIK, myelin breakdown due to a malfunctioning immune system is very much related to diseases like MS and ALS, among others.

    Which begs the question, if we could fix those disorders including restoring the myelin around the nerve fibers, could we keep people's brains working better for longer?

    • by yttrstein (891553) on Monday October 27 2008, @12:58PM (#25530603) Homepage
      We can, and the substances that have been shown to be effective on this have been around for quite a while, the most modern ones being things like phenylpiracetam and pramiracetam, whos alkaloids are a suitable replacement in myelin sheath generation in aging human brains.

      I expect this to suddenly be "news" in about five years.
      • Can these substances be used to help restore lost motor function due to the immune system attacking the myelin sheath of motor neurons? If so it should basically fix things like ALS, MS, MMN... I assume not, as those diseases are (to the extent of my knowledge) treated with totally different approaches?

        • by yttrstein (891553) on Monday October 27 2008, @01:59PM (#25531511) Homepage
          First, I have to say, take the following with a grain of salt, since it's anecdotal:

          Most of the research on the 'racetam family of bioactives has been done in Russia, and because of this there are both mistrusts and language barriers to overcome, but in doing so I discovered some pretty massively interesting studies all about specifically myelin sheath issues. So, since these substances are freely available in the US without any kind of prescription (unlike Russia, interestingly), I purchased a few and fed them to my mother, who is in the last couple of stages of post polio syndrome, which among other things (to put it in a nutshell) severely inhibits myelin effectiveness in nerve sheath maintenance. When she started the regimen a year ago, she couldn't walk at all and had great difficulty grasping things with her left hand, and was also in tremdous pain.

          Just a week ago she and I walked about six blocks to a restaurant, and then back. She can grasp things in her left hand fairly well at this point, and is in very little pain.

          I don't know myelin "helping" nootropics are the holy grail of neurological disorders, but they appear to have helped at least one person tremendously.
          • but they appear to have helped at least one person

            I'm not dissing you or your mother, but that could have been the placebo effect. Without a control group, we'll never know. I'm happy for you in any case, and I would say that if nothing else we need more research here.

            Interesting article [sciencenews.org]. This drug "reboots" the immune system, allowing myelin sheathes to reform. I'm waiting to see if these results can be duplicated; if so this stuff might actually be the holy grail you speak of.

              • Hmmm, I can't find the statistics right now, but for stroke victims, the amount you tell them they will get better makes much more difference than any administration of drugs.

                The placebo effect on brain development/neurogenesis/related is huge. IIRC the research I read was comparing "you will get perfect again", both with and without some drug (Valium?) to "you might get better, but you won't be as good as before" with and without the drug.

                No one ever got completely perfect again, but people who were told that they would fared better. These were reproduced a couple of times, and MRIs showed significant (yes, statistically significant) neurogenesis difference, although not by a wide margin.

                Note: I'm now completely offtopic, talking about loss of blood supply and permanent brain damage while TFA is talking about myelination.

    • could we keep people's brains working better for longer?

      To be honest, given that we have no real definition of what "intelligence" is, to say that people get less intelligent in some way once they get past 40 is reaching a bit. Granted there is a physical effect being observed, but people have lost significant hunks of their brains with little detrimental effect.

    • For those who would ask: Phenylpiracetam [wikipedia.org]
    • by mcgrew (92797) * on Monday October 27 2008, @01:18PM (#25530901) Journal

      Interestingly, AFAIK, myelin breakdown due to a malfunctioning immune system is very much related to diseases like MS and ALS, among others.

      Which brings up a point - no two people are alike. No two people age the same way. I know guys fifteen years younger than me who look older than I am.

      My uncle died of ALS (Lou Gherig's Disease). Most people are dead of this disease before age 65, he didn't even show symptoms until his eighties.

      Spme people's brains peak at age 30, some people's brains peak at 50. To say everyone's brains are the same at any given age is stupidly ludicrous.

  • by bloodninja (1291306) on Monday October 27 2008, @12:44PM (#25530327)

    This is probably what leads to a midlife crisis. One day you wake up smarter than you've ever been and go "holy shit, I've been a jackass all these years". Then you go and do something about it.

  • ...I have to say I expected a little more ;-)

  • by tftp (111690) on Monday October 27 2008, @12:46PM (#25530377) Homepage

    some people may think "life begins at 40," all it seems to do is slow down

    There is no contradiction, IMO. I know people who are so fast they don't have time to live, they are always five minutes late for something. Life begins when you can slow down, relax and think.

    • Coding too (Score:4, Insightful)

      by EmbeddedJanitor (597831) on Monday October 27 2008, @01:20PM (#25530925)
      Sure the young 'uns can sit up all night and crank out code fast, but quite often the older guys will be relaxing and thinking a bit more and come up with better code.

      But that might also be because by age 40 you'd probably have diverted into management if you were no good at coding.

  • by thermian (1267986) on Monday October 27 2008, @12:47PM (#25530401)

    Once, over a period of a week when I was in my twenties, I got repeatedly destroyed at chess by a guy in his eighties. Seriously, I have never been so utterly unable to outthink anyone in my life, and I'm a pretty good chess player.

    He started playing chess as a boy, and while he did tend to ramble on a bit, if his mind wasn't as sharp as it used to be, it must have once been able to cut diamonds...

      • by Knara (9377) on Monday October 27 2008, @05:24PM (#25534417)

        The New Yorker had an interesting article a few weeks back about young vs old geniuses, that your post made me think of. Let me see if I can find it....

        Ah, here it is [newyorker.com]

        From reading various things, I've come to the conclusion that brains are hard to generalize. Even assuming one of the million things that can go wrong with them doesn't, in fact, happen, they still develop differently from individual to individual, and that what we presume to be the normal way that people's brains "age" isn't necessarily so.

  • by schwit1 (797399) on Monday October 27 2008, @12:48PM (#25530407)
    Just like the Glucosamine Chondroitin scams. I'm seeing them now for pets.
  • Oh no! (Score:5, Funny)

    by T.E.D. (34228) on Monday October 27 2008, @12:48PM (#25530411)

    Being 41, I was rather dismayed to see this article. Even more upsetting was the fact that I then proceeded to left click on it, rather than my ususal middle-click to open it in a tab.

    Oh no! It's starting already!

      • Middle-clicking is becoming a new thing(?). You can middle click to open links in new tabs, middle click the tab to close the tab, that's just for web browsing. I have noticed that newer programs support new functions with middle clicking certain areas... I'm still waiting for support for an 8 button mouse though.

        Seriously, we have a 100+ key keyboard for the left hand, and 3 whole friggin buttons for my right hand? No wonder I started out life right handed and ended up becoming ambidextrous.
  • Ahem ... (Score:5, Insightful)

    by foobsr (693224) on Monday October 27 2008, @12:49PM (#25530447) Homepage Journal
    ... they base their result on a sample of 72 persons within an age range from 23 to 80.

    Science at its best.

    CC.
    • Re: (Score:3, Interesting)

      It's still science. Weak or strong statistacally, science is body of work based on "Cool! Hey everybody, check this out!" followed either by "Hey, that is cool!" or "Dork, you forgot to carry the one!" Sometimes both.
      • Re:Ahem ... (Score:4, Insightful)

        by Rakshasa Taisab (244699) on Monday October 27 2008, @01:03PM (#25530693) Homepage

        It's still _BAD_ science.

        • by Sockatume (732728) on Monday October 27 2008, @01:17PM (#25530897) Homepage
          The fuck it is. It's bad reporting. The actual research is all about how motor response speed correlates extremely well with myelin degradation, and discusses how this backs up the idea that myelin degradation is important in the aging of the brain and the resulting reduced physical ability. Even the press release, entitled "Physical decline caused by slow decay of brain's myelin" only mentions the 39-year figure once, and only in the context of this particular sample group, two-thirds of the way down the web page. 39 is the age at which finger tapping speed and myelin integrity both peak and begin to decline. At no point do the researchers claim that this has anything to do with cognative performance, let alone extrapolate it to say that there's some magic age at which mental function begins to decline.

          That story is a creation of the media which have decided to run with "brains work best at age of 39" for no readily appreciable fucking reason. Next time, hacks, save some effort and just put a bunch of words in a hat and make up the story based on those.
    • ... they base their result on a sample of 72 persons within an age range from 23 to 80.

      Science at its best.

      CC.

      They were the only ones in the hospital at the time.

    • Re: (Score:3, Informative)

      Okay, so maybe they are a little wrong and the actual age of brainy awesomeness is some other number between 35-45. That doesn't make the whole study wrong. What is interesting is that the age they found was 39 instead of, say, 23. We shouldn't start publishing their results in schoolbooks all over the world yet, but the results are interesting and invite further research on the subject.

      Don't expect EVERY study to involve thousands of people, that would be way too expensive. Instead you check interesting hy

    • Re:Ahem ... (Score:5, Funny)

      by Chapter80 (926879) on Monday October 27 2008, @01:47PM (#25531341)

      ... they base their result on a sample of 72 persons within an age range from 23 to 80.

      What do you expect? The researcher was in his 40's. He was much better a few years back...

  • by NoNeeeed (157503) <slash@@@paulleader...co...uk> on Monday October 27 2008, @12:50PM (#25530461) Homepage

    From what I have read, this only appears to apply to the speed of thought, which impacts on our reaction speeds. This would chime with most people's experience of ageing.

    What I would be interesting in is whether it actually has a knock-on effect on the quality of cognitive ability. Does thinking faster equal thinking better?

    Also, I wonder if the increase in experience is enough to overcome the reduction in reaction speeds. For example a 17 year old may have a great reaction speed, but that doesn't automatically make them a better driver than a 40 year-old with 20+ years of predicting the motion of objects travelling at speed and planning accordingly.

  • What about exercise? (Score:5, Interesting)

    by rrohbeck (944847) on Monday October 27 2008, @12:56PM (#25530563)

    It is well known that regular intense exercise has a profound impact on aging and brain performance.
    I can't take a report serious that doesn't take the effect of exercise into consideration and doesn't even mention it.
    So does 39 apply to complete couch potatoes? Average Americans with little exercise? Athletes?

  • Fatty skin? (Score:4, Funny)

    by Comboman (895500) on Monday October 27 2008, @01:09PM (#25530777)

    "The loss of a fatty skin that coats the nerve cells, called neurons, during middle age causes the slowdown, experts say.

    Loss of fatty skin? When I hit middle age, that's when I started getting fatty skin.

  • Not mine. (Score:3, Interesting)

    by mcgrew (92797) * on Monday October 27 2008, @01:13PM (#25530827) Journal

    Brains Work Best At Age of 39

    I was in a bad car wreck at age 24, dropped ten points on my IQ. Lucky for me it was 142 before the wreck.

    It seems to have gotten progressively better since then, until a few years ago when it kind of reached a plateau; I don't think I'm as creative as I was a few years ago.

    When the sheath deteriorates, signals passing along the neurons in the brain slow down. This means reaction times in the body are slower too.

    That doesn't mean you're not as smart, it means your reflexes are slower. You're born as intelligent as you'll ever be; your capacity to learn is at its maximum. However, you are also as ignorant as you'll ever be, as you know absolutely nothing whatever.

    A middle aged professor I once knew was fond of telling his students "I've forgotten more than you've ever learned".

  • Fastest != Best (Score:4, Insightful)

    by Doc Ruby (173196) on Monday October 27 2008, @01:31PM (#25531095) Homepage Journal

    Just because older brains don't necessarily work as fast as younger ones doesn't mean they don't work better. Plenty of better thinking is slower than the fastest stuff, like jumping to conclusions. And the older brains have lots more information and habits that can be more powerful than the newer ones. This is known to humans as "wisdom".

    Besides, just getting to the wrong answer faster is not "better".

    Just some more reasons people say "age and guile will beat youth and talent any day". Even if younger people just zip around without realizing it.

  • Noise (Score:4, Interesting)

    Being 44 years old now, I have noticed that I'm not able to think as clearly as I did in my early thirties. In my self analysis, however, I find the biggest culprit is "brain noise." When I think about something, irrelevant associations will pop in with much greater frequency, distracting me from "pure" concentration. Which makes me wonder if it's simply a natural consequence of life: more and more detail is stored away in my head. A younger person with a relatively "empty" head isn't as distracted by all the useless dreck and is able to form thoughts more cleanly.

    Even as I type this post, my lifetime of experience keep popping in with tangentially relevant information, not to mention songs triggered by phrases, movie quotes and other useless crapola. :D

    I've actually wondered if there are mental exercises such as meditation that might help to quiet all the noise.

    • Re:Noise (Score:4, Informative)

      by FooGoo (98336) on Monday October 27 2008, @02:26PM (#25531847)

      Vipassana or insight meditation is what you are looking for.

    • Re: (Score:3, Interesting)

      When I think about something, irrelevant associations will pop in with much greater frequency, distracting me from "pure" concentration.

      I've actually wondered if there are mental exercises such as meditation that might help to quiet all the noise.

      I know the kind of noise you're talking about, and I would recommend a different approach - rather than learning a technique to "block it out", instead learn techniques for effective brain "multi-tasking". You can keep a very strong focus on the topic at hand, as well as let the useless dreck wander through without interrupting you (but if something useful floats by, you can grab it and run with it).

      My recommendation for this would be to overly excite your brain for a bit with LOTS of useless extra informa

  • by haruchai (17472) on Monday October 27 2008, @02:49PM (#25532169)

    Historically, their most significant work is done before age 30.

    • Re: (Score:3, Insightful)

      More than likely you are now wise enough to know that you don't know everything.

    • by theaveng (1243528) on Monday October 27 2008, @01:06PM (#25530743)

      There is No "one" point where the body stops working. Different systems age at different rates:

      - the reproductive system peaks somewhere around age 16 or 17 (lowest risk of birth defects)
      - the *desire* for sex peaks just prior to menopause for women (circa age 35) and apparently never ends for men ;-)
      - flexibility (ala gymanasts and skaters) peaks at 15 and ends around 25
      - reaction time peaks at 30
      - and now it's revealed that the human brain peaks just prior to 40 - after which the neurons' tendrils start falling apart (like an old rubber hose).

      • by Bob-taro (996889) on Monday October 27 2008, @02:32PM (#25531933)

        - flexibility (ala gymanasts and skaters) peaks at 15 and ends around 25

        Flexiblity ENDS at 25? Is that some sort of pun? I never was very limber, but I'm over 40 and it's not like rigor mortis has set in yet.