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Scientists Move Closer to Human Therapeutic Cloning

Journal written by stemceller (975823) and posted by samzenpus on Wed Jun 20, 2007 10:11 PM
from the send-the-therapeutic-you-to-work-day dept.
"Human therapeutic cloning has moved a step closer after U.S. researchers said they had successfully created embryonic stem cells from monkey embryos. Scientists told a stem cell research conference in Cairns this week that they had successfully created two batches of embryonic stem cells from cloned rhesus monkey embryos."
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  • If you're a Religious Conservative, which is worse:
    A) Human stem cells taken from humans
    B) Human stem cells taken from cloned monkeys
    C) Yes

    I'm guessing that they're going to go with C
    Mostly because I can't imagine they'll like cloned monkeys
    • Re: (Score:3, Insightful)

      The only reason they oppose embryonic stem cells is because of the possibility of it affecting abortion case law.

      Of course, they'll likely decide this is the work of satan because it could maybe lend credence to "evilution".

      The *real* problem here is religion.

      "There can be but little liberty on earth while men worship a tyrant in heaven."- Robert Green Ingersoll
      • There's a fundamental difference between religion and church.

        Pun intended.
      • Re: (Score:2, Insightful)

        No, you've got it backwards. The only reason some people support the use of embryonic stem cells is because of the possibility of it affecting abortion case law. Why not use adult stem cells, which have already been shown to be medically useful? The problem is that the pro-abortion lobby wants to use the issue of possible cures to get people to reject the humanity of human embryos. That's why you never hear embryonic stem cell research supporters talk about the benefits of adult stem cells: it doesn't f
        • Re:Which is worse (Score:5, Insightful)

          by Adult film producer (866485) <van@i2pmail.org> on Thursday June 21 2007, @07:40AM (#19592911)
          It's the killing of a young human being.

          Actually, that is not the case. It's the destruction of a blastocyst, which is a compilation of 70-150 cells. These are often thrown out/discarded in fertility clinics. They are definitely not human. Here's a picture of one,

          http://www.iscr.ed.ac.uk/outreach/images/Human-bla stocyst.gif [ed.ac.uk]
          • by BigDogCH (760290) on Thursday June 21 2007, @08:14AM (#19593269) Journal
            Oh the humanity!!!!

            That little glob could be the next OJ Simpson, or Professor Snape!

            If that is a human, than I think I may have just picked a human out of my nose this morning. Now I am going to find it, and call it Freddie.

            Every sperm is sacred! Save me Jebus!
              • At some point I was a sperm in my father and an egg in my mother, does that mean that my mother is a murderer every month (or my father one, uh, I can assume more than that ::shudder at the thought::)
          • Re: (Score:3, Insightful)

            GP should not be modded "Troll" or "Flamebait". They are giving a reasoned argument in response to somebody else on the other side of the issue. This shows a true lack of intellectual integrity on the part of some moderators here. In order to maintain internal consistency, pro-life people must be opposed to the destruction of humans in the earliest stages of development, and pro-choice people must be in favor of destruction of human life in the earliest stages. You may like to argue that a baby is just a zy
        • Why not use adult stem cells, which have already been shown to be medically useful?
          Because thousands of embryos get thrown out everyday in fertility clinics, and I don't like things going to waste.
    • True, but what about a cloned monkey with five asses?
  • Keep in mind (Score:5, Informative)

    by Short Circuit (52384) <mikemol@gmail.com> on Wednesday June 20 2007, @10:26PM (#19590077) Homepage Journal
    Rhesus monkey stem cells may not be entirely compatible with human nuclei, so this by no means brings the human stem cell debate closer to an end.

    Cell workings differ slightly between species. Different proteins may be present, etc.
    • Re: (Score:2, Interesting)

      by Anonymous Coward
      Actually, as non-biologists, y'all seem to be missing the point.

      They have used 'emptied' egg cells and injected 'adult' nuclei. The young, messed-up embryos that resulted were dissected (split clump of cells into individual cells) and they were able to recover viable 'embryonic' stem cell lines which have totipotency and near immortality, in terms of continued cell division.

      The importance of this is important because (a) it is the first primate example and (b) it is from an adult nucleus. In the former, p
  • by Kingrames (858416) on Wednesday June 20 2007, @10:28PM (#19590101)
    Therapeutic Cloning?

    WTF is that supposed to mean?
    You're cloning yourself... to feel better?
    If you don't feel good, why clone yourself?
    • by niceone (992278) * on Wednesday June 20 2007, @10:34PM (#19590151) Journal
      If you don't feel good, why clone yourself?

      To have someone to share the misery with?
      • All you really need to do to get company is to open up a cold can.
        's cheaper than therapeutic cloning, I'd imagine.
      • Therapeutic.. (Score:2, Interesting)

        by Anonymous Coward
        Thing is that, e.g. if you were predisposed to get Diabetes (i.e. to show its symptoms) at the age of 30, you'd have to wait 30 years for your clone to share its misery with you. Jokes aside you might need to wait a couple of year until your clone can share his/her kidney with you. A more useful approach would be to grow organs out of stem cells instead of full human beings which would create a host of new problems, e.g. visual identification in case of a crime committed ("It wasn't me! It was my evil twin
    • Re:Therapeutic? (Score:4, Insightful)

      by MMC Monster (602931) on Thursday June 21 2007, @06:31AM (#19592443)
      The idea is that: You feel sad because you lost a leg. You have yourself cloned to create a new leg. You transplant the leg from the clone to yourself so you don't feel sad anymore. Providing, of course, that you can convince the clone to give up a leg for you.

      In real life there are more issues (not withstanding the moral issues if the clone is allowed to develop a brain). For instance, we are not purely a product of our genes. Otherwise identical twins would look identical until the moment they both suffered a heart attack and died. If you need a solid organ, it needs to be grown in a viable host. It's likely impossible using current (or near-future) technology to create a viable host that does not have brain activity.
  • can only be used by Monkey boy Steve Ballmer [google.com].

    It may one day be possible to do this with human beings. Until then animal testing is in order.

  • by Ungrounded Lightning (62228) on Wednesday June 20 2007, @10:36PM (#19590169) Journal
    A switch to using polarized light in labwork instead of dye and ultraviolet light traditionally used to identify cell chromosomes may have led to the breakthrough, ...

    So for years the scientists have been finding the chromosomes to transplant by:

      - Flooding the donor cell with a fluorescent dye that bonds to DNA, then

      - Shining ultraviolet light (i.e. ionizing radiation) on the cell, causing the dye to fluoresce (and also dump enough energy into the DNA molecule to break molecular bonds and produce free radicals in the nearby area).

    And then they wondered why, after they transplanted this DNA into the denucleated egg, the resulting cell didn't work right.

    Good grief!
    • thats the problem of overspecializing. often one cant see the problem because one do not have the relevant knowledge. in this case it may well be simple for someone with experience in nuclear physics to spot the problems with the process. but for someone thats worked with biochemistry for the same amount of time, it may not be.

      modern society are a bit like machine, each individual have a very specific task to perform and are groomed for that task from a very early age. if everyone with knowhow about said ta
    • Re: (Score:3, Interesting)

      You've got this backwards - the people working in this field are fully aware of the effect of dye staining and UV on DNA. They don't stain the nucleus of the somatic cell, they stain the nucleus of the egg (to make it easy to get rid of). Supposedly the problem isn't DNA damage, but (perhaps) damage to unspecified 'programming factors' elsewhere in the egg.
  • Right now, Republicans are leary of harvesting human clones for parts, and Democrats are all in favor of it, but just wait until someone makes $1 off of it. Then, the tables will turn.

    It's all going to start when someone figures out how to clone men but with giant penises, for easy transplant. Why compete over cars, houses, plots of land and computer upgrades when you can just go buy the real deal? In America, EVERY MAN will be a porn star. There will be billions of dollars made there.

    From there, we'll get on to using human skin and hair for clothing, and human bones as a proxy for ivory. At first, it will be a status symbol. You really could have a lampshade made out of human skin, or even a football for junior or a jacket for the mrs. But soon, with enough venture capital, human clones will be mass produced and harvested like so many sheep, and even more billions will be made.

    Eventually, there will be, within the USA alone, a 200 billion dollar a year industry dedicated to the production, harvest, and manufacturing goods based on harvested clones. At that point, just as you once saw liberals hail the progress of animal antibiotics and industrial farming and then turn to an imaginary better day of all natural organic everything, you'll see liberals lamenting the devaluation of the human body, whereas, conservatives will merely say they are free and supporting consumer demand. Then liberals will eventually say the masses are stupid for supporting a human cloning industry and demand federal action to slow it down or stop it, write thousands of books decrying it, and support an endlessly array of Democratic candidates that promise to reform it but never really do. In the meantime, conservatives will argue the cloning is natural, its our right to do so, and its part of God's plan anyway, and to support their position, they will dredge up every last salamder that can regrow its own tail, every asexually produced thing in nature, and every supporting phrase in the bible. Oh yes, Jesus was very much in favor of harvesting clones, if you know which 4 passages to read.
    • Whoa...Johnny, go take your meds man...
    • Re: (Score:3, Insightful)

      I hope I'm not making a mistake by taking your post seriously...

      Cloning for parts will not be done by growing a whole new organism and hacking off whatever the originator wants. That would be an abomination that anyone of any political orientation could recognize. What will be done is that (non-embrionic) cells will be encouraged to grow the appropriate tissues or organs, without developing a nervous system. With this sort of technology, only some of the religious nut cases will still insist that a being w

    • You have an interesting point but you forget how fucking creepy it is. People don't like the thought of a human skin coat, let alone a lamp shade. It's just too fucked up. Now if you're talking organ donation.. well yea, I can dig that. We'll see that for sure and in the US it will obviously be based around greed not need.

      As for the porn star penis. Personally I'll stick with mine, I don't need some 12 foot dick only good for breaking coconuts in half with, any guy who isn't a complete ignorant fuck knows t
    • Slippery slope fallacy ? You don't say... Fun read though, especially towards the end :D
      • Men want huge penises to whack off with -- who cares how the women feel about it?

        But seriously, most people are superficial, and once stem cells show the ability outperform Botox, plastic surgery, RetinA, monoxidil, Oil of Olay, l'Oreal cosmetics, Ben Gay, etc, then you won't be able to beat the customers off with a stick. (Or even with a big penis to slap them with)

        Women are more insecure about their looks than men. They will kill to get that youthful teenage wrinkle-free skin. They will go to back-alley a
        • They will go to back-alley abortion clinics to harvest embryonic cells from themselves.

          Embryonic stem cells don't come from abortions, let alone back-alley ones. Scientists harvest them from a few day old zygotes, and you can't perform an abortion only a couple of days after conception. Stem cells come from embryos made in a lab, either specifically for that purpose or excess from fertility treatments that would otherwise be thrown away.

          Embryonic stem cell research has nothing to do with abortion. T

  • Let's get serious, (Score:4, Informative)

    by the_kanzure (1100087) on Wednesday June 20 2007, @10:47PM (#19590233) Homepage
    Five minutes of thoughtful searching brought up useful, important information for anybody willing to take these sciences and technologies seriously. The National Institute of Health (NIH) stem cell page [nih.gov] has some paper abstracts as well as listed universities with programs in these United States (and some online resources [neu.edu]). Useful sources of information at this bibliography re: human reproductive cloning [nap.edu], at Boston University [bu.edu] and this one [wa.edu.au]. CiteSeer popped up the paper on nuclear transfer / human cloning [psu.edu]. Apparently there's at least one dedicated research foundation [stemcellre...dation.org] out there.

    Granted, most of these links are preliminary- check those deep databases, like over at PubMed Central, for those detailed reviews of the state of the art. And just for kicks, one last link [bioinformatics.org] which (still) impresses me.
  • Bush's Braincells (Score:3, Interesting)

    by Doc Ruby (173196) on Wednesday June 20 2007, @10:58PM (#19590297) Homepage Journal
    Bush wants you and your people to die without stemcell therapy [google.com].

    Of course, he'll get any he wants, from some other country if that's necessary.
    • by RMH101 (636144) on Thursday June 21 2007, @06:54AM (#19592587)
      from http://www.theregister.co.uk/2007/06/21/politics_s tem_cells_veto/ [theregister.co.uk]

      President Bush has used his veto to kill another bill that would have lifted some of the restrictions on research using human embryonic stem cells.
      The news has been greeted with dismay, but not surprise, by the scientific community.
      In announcing his use of the veto, Bush told reporters: "Destroying human life in the hopes of saving human life is not ethical."

      Um, hello George...presumably it's OK if it's for oil?

    • Won't someone think of the adults?
      • The news not-so-long-ago was that they could now create stem cells without going anywhere NEAR an embryo.

        http://science.slashdot.org/article.pl?sid=07/06/0 6/1924232 [slashdot.org]

        The summary says they can't be safely used for transplant, but then, the day before they discovered that, they thought it couldn't be done at all. Given time, we'll we creating stem cells as-needed from patients in surgery, and in a short time later, use them to replace the damaged area. Skin grafts will become amazingly easy, and replacing a
  • Whew!! (Score:4, Funny)

    by rts008 (812749) <rts008@@@hotmail...com> on Wednesday June 20 2007, @11:00PM (#19590305) Journal
    Damn good thing I like bananas, and trees, and Tarzan, and especially Jane!

    When the Labcoats attack you, prepare to fling the poo,
    Monkey see...Monkey do(doo)!
  • by davidwr (791652) on Wednesday June 20 2007, @11:03PM (#19590329) Homepage Journal

    Oh, give me a clone
    Of my own flesh and bone
    With its Y-chromosome changed to X
    And when it is grown
    Then my own little clone
    Will be of the opposite sex.

    (Chorus)
    Clone, clone of my own,
    With your Y-Chromosome changed to X
    And when I'm alone
    With my own little clone
    We will both think of nothing but sex.
    -Randall Garrett, additional verses [commonplacebook.com] by Isaac Asimov

    Now can anyone accelerate the aging process? By the time she's 18 I could be dead.
  • Real "Therapeutic Cloning" would be cloning Capt. Janeway and Seven Of Nine for me so I could get massages after long days at work.

    Now *THAT* would be therapeutic!
  • I guess we've evolved to the point where we can be intelligently designed...
  • The recent advance of creating stem cells from skin cells (using embryonic stem cells cultured in the lab from previously collected stem cells) suggests to me that there are a potentially large number of other methods to obtain/generate these cells that does not involve the destruction of viable human embryos.

    I have also found it interesting that embryonic stem cells, apparently, can be taken from umbilical cords and placental cells. Why is this ignored in research (or is it a case of a percentage of resear
  • Why does my clone smell like burning rhesus monkey?
  • Some one giving the right to create life for the entire purpose of destroying it.

    OR

    Some on rejecting the right to create life for the entire purpose of destroying it, and some doctors doing it anyways?

    Either way, creating life for the sake of destroying it is not moral, in my opinion. I'm not religious in any case, as I'm not a "believer", but as a father of two boys, and a person with respect to choice as well as life, I couldn't give something like this the go-ahead.

    A woman getting pregnant and choosing
    • I bet your body can sustain other life. A lot of your digestive tract is other life.

      Parasites? Other life..etc.
    • not "full person" cloning. more like "clone a new kidney that is an exact genetic match for me so i don't need anti-rejection drugs".
    • Re: (Score:2, Insightful)

      Let's weaken the gene pool some more. We already have people living to reproductive age with characteristics that 50 years ago nature would have 'selected against'.

      Posts like the one above always make me laugh because the poster always assumes they are part of the strong, smart, or whatever desired characteristic. Take your timeline back 1000 years, maybe your current traits would have been selected against.

      Have you ever gotten sick and taken an antibiotic, required stitches, or maybe have a broken bone