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Sleep Deprivation Increases Brain Activity
Posted by
Hemos
on Fri Feb 11, 2000 06:49 PM
from the this-explains-my-college-years dept.
from the this-explains-my-college-years dept.
SL33Z3 writes "Researchers at the University of California at San Diego have found increased brain activity in areas of the brain that otherwise stay inactive. The longer the students went without sleep, the more activity was found. Research found students to have better recollection after long periods of sleep deprivation. Check out the release here. " Heck, combine this with the news about caffeine and I'm all set!
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One in Ten Americans Are Chronically Sleep Deprived 329 comments
WirePosted writes "A CDC research study released this past week indicates that the physical and mental health of many Americans is being adversely affected by a lack of sleep. According to the study, a part of the organization's Morbidity and Mortality Weekly Report, one in ten US citizens are consistently failing to get enough sleep every night. Almost 40% of the people surveyed didn't get enough sleep for more than a week every month. The article notes that this trend can have far-ranging implications for health beyond simple fatigue."
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Too much sleep? (Score:1)
Although I get an average of 5 hours.. but hey, combine that with coffee and you've got maximisation of time and efficiency
Re:"Unrecoverable brain damage" (Score:1)
And about cells dying and others taking place - that's also not true. Neurons have several axons forming synapses, and if one dies, the axons go with it - if one were to take it's place, it would have lost all the connections of the previous one. And since learning, memory, our personality, etc, is all due to the way the various axons are arranged, after some time we'd have these parameters altered: different personality, loss of memory, etc, and that does NOT happen.
Sure, brain cells die, but with aging, and they are not replaced with new ones.
-- Electron
Re:Crystal Meth increases brain activity too. (Score:1)
But yeah, that would scare the hell out of me. Four days on and three days off? Geez, how long can someone's body take punishment like that?
---
pb Reply or e-mail; don't vaguely moderate [152.7.41.11].
Yeah, so? (Score:1)
Severe sleep deprivation resembles an acid trip.
More brain activity is not always a good thing, unless you like having your neurons cross-linked.
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pb Reply or e-mail; don't vaguely moderate [152.7.41.11].
Re:Longest without sleep? (Score:1)
I was trying to stay awake for the whole week, and failed. But I had a lot of fun, anyhow...
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pb Reply or e-mail; don't vaguely moderate [152.7.41.11].
Sleep Deprivation = Brain Activity = Hallucination (Score:1)
The extra activity is hallucinations..
Ask any Crack/Meth/Coke-head.
Here's something I noticed (Score:1)
You know that if you stay up past the point that you "get sleepy" that eventually the sleepiness wears off, and you get what is commonly referred to as a "second wind". This process seems to continue (at least for me) in a cycle (get sleepy, get nth wind, get sleepy, get n+1th wind, etc...) where the lengths of time between periods of sleepiness (aka: the "winds") get shorter, and the periods of sleepiness get longer.
Now, I've noticed that at some point, (generally halfway through either the 2nd or 3rd wind) I seem to be a heck of a lot more creative. I also get a heck of a lot more work done.
But, it gets increasingly hard to concentrate on a single task - my mind tends to wander a lot as the condition wears on.
Coffee (and I'm assuming other stimulants as well) seems to have a lengthening effect on the "winds", but when it wears off, the "winds" shorten dramatically. (sort of like what we're all expecting to happen to Dick Clark - at some point he's going to age 60-100 years in a matter of minutes...I hope he's on camera...)
This is just personal observation, of course, and has absolutely no medical founding (IANAD)
(Sort of like the observastion that while I don't tend to eat red meat much, I crave it when I'm injured - almost like I'm looking for raw materials to rebuild the broken parts...)
And yes, I'm aware that this post tends to ramble a bit...I'm on my 4th wind and ready for bed
Attempt to answer a few questions running around (Score:1)
First of all, there are parts of your brain that have increased activity during sleep, especially in the brainstem (note that most researchers sperate sleep into slow wave and REM, since REM is really strange, but this statement applies to all sleep).
Second of all, past sleep dep studies have shown that the main symptom of sleep dep is. . . feeling sleepy. Yes, cognitive functions are impared, but significantly less so than expected (it is suspected that most of those effects are due to attention problems rather than actual cortical processing issues).
Third, the need for sleep decreases as you age, although I can't point to any studies on sleep dep. in the elderly (it is known, however, that significant sleep dep. in the elderly mimics Alzheimer's in that it causes misdiagnoses).
Fourth, I suspect the 17 days rat sleep dep. death figure is due to use of the water tank method of sleep dep., where a rat is placed on a very small platform in a tank of water, such that it falls in the water if it falls asleep. This is highly stressful in addition to depriving sleep. An experiment where the bottom of a cage was rotated (the walls stayed still, so the rat was bumped by the walls which woke it up and it had to walk some before it stopped) when EEG signals indicated sleep for the experimental rat (a control rat was also in the cage but was allowed to sleep; I did not suffer ill effects) showed that it took 30 days for the rat to die. That's something of a nitpick, but implies that stress might also be deadly.
Finally, to counter the story of the DJ, let me tell you the story of the 17 year old kid who stayed awake for 264 hours (11 days) in an attempt to break the world record (dunno if he succeeded) in 1965. By the last day he was really sleepy but could still perform tasks (the kind that scientists give people, I don't know specifics). Afterwards he slept for 14 hours 40 minutes straight, then was fully recovered with no aftereffects. Also, Kales in 1970 performed an experiment where 4 subjects were kept awake for 205 hours. They suffered eyelid tremors and decreased performance (which was suspected to be due to lack of motivation) and had a big REM rebound (lots more of their sleep was in REM than normal) for 4 days, then also fully recovered.
A good book on the subject is "Sleep" by J. Allen Hobson (an expert on the subject who works at Harvard).
Brynn, who suspects that the DJ in question already had some stability issues
Ginseng (Score:1)
Hmmm... (Score:1)
Re:Glucose: Sleep's role in our physiology (Score:1)
Re:Sleep Deprivation as a torture technique (Score:1)
-- Faré @ TUNES [tunes.org].org
Re:Does that mean... (Score:1)
XFS might be pretty cool. I could really use the GRIO (Guaranteed Rate I/O) whenever I trying to explain things to people. No more stuttering while I'm trying to remember what I wanted to say. ;-)
--Joe--
Re:Does that mean... (Score:1)
Do you suppose we can get Stephen Tweedie to port ext3 to neurons once he's done?
--Joe "Journal Neuron Not Found" Z.--
Re:Longest without sleep? (Score:1)
Driph
"Whatever you can do, or dream you can do, begin it.
Re:Sleep Deprivation can also kill. (Score:1)
--
Burning the midnight oil (Score:1)
Why? Traditionally, it is attributed to our carnivorous nature (anyone who claims humans are vegetarians has clearly not researched this well enough, only even in the last few thousand years have humans become omnivorous). Humans still contain the basic animal instinct to hunt. Hunting was best done at night obviously for the surprise effect (which unfortunately works both ways!), and hence a few hundred thousand years of evolution later and we are better coders at night.
Of course, sleep deprivation is counterproductive, what I mentioned rather refers to working late. When I'm working on big projects I tend to get into the habit of working late and sleeping late. I can't count the number of times that working through being exhausted has resulted in bad code, regardless of time. If I'm tired at noon, I write crap at noon. I think the true mark of a coder is to dynamically alter your sleep cycles between "human" mode where you sleep at night and week up in the morning, and "machine" mode where you sleep in the morning and wake up in the afternoon.
I think the survey was taking a more narrow slice of this, not quite what the submitter had in mind. Still interesting and provacative though. Remember, if its ambiguity raises too many eyebrows, a clarification will probably follow.
I see dead people... (Score:1)
Is this a good idea to tell people:
(define direct_relationship(sleep, brian_activity))
proc less_sleep
begin
inc brian_activity
end
oh god I need a little more sleep...
for(i=10;i100;i+=10)sleep(i);
when:: little_sleep(me)
segmentation fault... woof woof
MPAA (Score:1)
Well, at least we know the MPAA isn't losing any sleep...
Re:"Unrecoverable brain damage" (Score:1)
READ THE ARTICLE... (Score:1)
"Subjects had fewer correct answers and omitted more responses when sleepy than when rested."
Does that mean... (Score:1)
What a mess.
(on the serious side, do we really know what sleep is for, anyhow? Perhaps this is similar to a hard drive thrashing when the filesystem has gotten too fragmented. More overhead required to the do same thing...)
Re:Yeah, so? (Score:1)
I'd say sleep is a dangerous drug
-Serfer
Re:Longest without sleep? (Score:1)
"I can only show you Linux... you're the one who has to read the man pages."
Re:much worse side effects (Score:1)
Re:Yeah, so? (Score:1)
Re:Not EXACTLY like it sounds... (Score:2)
In extreme cases, brain cells can even be killed by overexcitation, although personally I'm only aware of drug models for this phenomenon.
Oxygen deprivation effects are partially due to excitotoxic effects. The malfunctioning (due to oxygen deprivation) neurons dump NMDA which causes neighboring neurons to self destrict. That's why there was interest in NMDA antagonists. That is anso a partial explaination for barbituate coma reducing brain damage due to hypoxia (if the barbituates don't kill you, of course).
Along with decreasing life expectancy (Score:2)
Sleep Deprivation != Acid Trips ! (Score:2)
I have many episode of sleep deprivations before, and I took acid many times in my younger days too.
What I can is that those two things are NOT the same.
Brains are like muscles (Score:2)
Muscles fire (contract) individual fibers to provide the needed amount of force. A fiber either fires, or it does not. After a fiber fires, it needs to rest and heal.
Sore muscles result from many fibers needing rest and healing. Muscle fatigue comes from many fibers having fired, and few being left available to keep the work going.
The speed with which muscle fibers recover is proportional to their level of conditioning. So an athletic person is ready to go again sooner that a sofa-spud.
What does this have to do with brains?
A conditioned brain is able to recover from effort more quickly, while a stagnant one needs a long weekend.
A brain that has used up it's 'normal' operating capacity (analog to 'conditioned' fibers) will start to recruit typically unused areas to keep the work going. Sleep deprivation is a way of keeping the normally used areas from getting adequare recoup time, thereby forcing the 'lazy' areas to take up some slack.
Sleep deprivation cycles, along with an inter-disciplinary training regiment (variance in modes of thought, analytical, creative, perceptive, linguistic, mathematical...) is for the brain exactly like cross-training is for the body.
And it sounds suspiciously like going to college.
Sleep's role in our physiology (Score:2)
It is obviously a necessity for the brain. Perhaps for consciousness to occur, there have to be periods of unconsciousness for some kind of routine "maintenance" that the brain's neural network performs on itself, somehow tied in with dreams.
I have absolutely no background on this - the above is just my random musings as I started learning about neural nets and AI. I was hoping to start a discussion or catch the eye of someone who has studied this extensively. What is the current state of human knowledge about sleep? Is it still mostly a mystery?
--
grappler
Glucose: Sleep's role in our physiology (Score:2)
A few years ago someone wondered: "Why are there no higher animals which do not sleep?" It clearly would be of great evolutionary advantage to not have to sleep. So there must be some very basic reason.
Answer: Brains use more energy than blood can deliver. The purpose of sleep is to recharge energy.
Mixed with neurons are glial cells, which store glucose during sleep. They then supply glucose to neighboring neurons while the brain is awake, supplementing glucose from the bloodstream.
When the energy is exhausted, neurons stop working properly. That's why there are hallucinations (particularly in pattern-matching neurons such as peripheral vision). It's probably also why the brain secretes chemicals which increase blood flow -- it's trying to get more glucose to keep functioning during whatever crisis is keeping it awake.
So, why might areas which are normally quiet showing more active in this study? Maybe because the blood flow has been increased in the exhausted areas, and also the neighboring cells which were least-used are now trying to activate because their exhausted neighbors can't work?
This paper does not seem to be on the net, so see Google search [google.com] of related comments.
Re:Glucose: Sleep's role in our physiology (Score:2)
Even very primitive animals sleep, although they don't have the need for as much maintenance. Apparentlyt we're all suffering from the same energy delivery deficit.
Re:Sleep Deprivation can also kill. (Score:2)
Re:Post wrong? (Score:2)
True story: I've been through officer training for a certain Army (er... figure it out). As trainees we were sleep-deprived for 4 weeks: an average 5 hrs of sleep a day, with an occasional Sunday 6 or 7 --this while exercising 4-5 hours a day, doing chores, being on duty, etc. etc, for the remainder of the day... During Week 3 I was sitting in a nice, cozy, warm room taking notes for some class. At that point, I was halucinating at night or early in the morning pretty regulary (in fact this was a common experience among my class-mates). But that day, while I was taking notes, I fell asleep. Writing. Notes. I was woken up --by my trainer no less-- and found out that I had written down my dream/halucination/what have you. Not much, a dozen words or so and then a squiggly line trailing off...
I should have kept that notebook. But I have never been more scared for my own well being before or since.
Yeah, you go and try out the poster's theory...
engineers never lie; we just approximate the truth.
yeah same thing (Score:2)
#----------------------------
$mrp=~s/mrp/elite god/g;
and yes... (Score:2)
(selling software doesnt make me enough money yet heh)
#----------------------------
$mrp=~s/mrp/elite god/g;
Ages of subjects? (Score:2)
Also, how did the study compensate for time of day? Many teens do not function well until late evening, and some researchers would be mislead to believe that it was sleep-deprivation causing the increased performance, not simple circadian rhythms.
In addition, I would expect people at all ages to have a small performance boost around morning -- when they would normally be getting up. This would be the body "thinking", "Crud, I guess I'm not getting any sleep tonight, might as well try to last until tomorrow evening".
--
Re:hell yeah (Score:2)
I've noticed that I can churn out code efficiently while tired, but I have more trouble searching for bugs and trying to solve complex algorithmic problems [usaco.org]. Is the same true for you?
I think our brains are designed to do repetitive tasks efficiently while tired, but are better at complex problem-solving while awake and relaxed.
--
"Unrecoverable brain damage" (Score:2)
There is a catch, however, and its the reason scientists once thot no brain cells could ever be regenerated... they need acetylcholene. Acetylcholene isn't usually found anywhere in your body except one place - the protective "lining" of brain cells. So when it goes to regenerate one, it rips an old one apart and builds the new cell inside, so it seems like no progress is being made. There is one food that contains acetylcholine, though. Fish! It really IS brain food! (I'm not joking, BTW) You can buy choline tablets too at health food stores. Lots of people call it a "smart drug" but it doesn't increase intelligence, it simply stops the brain from autocannibalizing cells when regenerating. Nootropics (smart drugs) is an interesting field. Most are just like caffeine spinoffs (keep you more alert) and a lot are just lies in a bottle, but there seems to be a lot of study done on acetylcholene.
Esperandi
Slashdot deprivation (Score:2)
A team of researchers from the UCSD School of Medicine and the Zelot Affairs Healthcare System, San Diego used functional magnetic resonance imaging (fMRI) technology to monitor activity in the brains of Slashdot-deprived subjects performing simple verbal learning tasks.
They were somewhat surprised to learn that regions of the brain's prefrontal cortex (PFC) displayed more activity in direct correlation with the subject's sense of Slashdotness; the Slashdotier the subject, the more active the PFC.
Furthermore, the temporal lobe, a brain region involved in language processing, was activated during flaming previous posts in troll subjects but not in Slashdot deprived subjects. Additionally, a region of the brain called the parietal lobes, not activated in troll subjects during the posting exercise, was more active when the subjects were deprived of Slashdot. The parietal region normally performs somewhat different functions in the learning process than the temporal region. Although subjects' memory performance was less efficient with Slashdot deprivation, greater activity in the parietal region was associated with better memory.
"Only in recent years have we begun to realize the prevalence and severity of Slashdot deprivation in our population, with a significant number of people doing first posts work, suffering from karma lag and so forth," said J. Natalie Portman, M.D., professor of psychiatry at the UCSD and the San Diego VAMC, and an author of the Flamebait paper. "Yet, we don't know very much about how Slashdot deprivation impairs sexual performance, and how precisely the brain reacts to lack of Slashdot. These findings are just a beginning, and as we learn more, perhaps will be able to devise interventions to alleviate the behavioral impairments associated with lack of Slashdot."
Re:All Set? (Score:2)
Misleading (Score:2)
Me I take the safe route, I view non-sleep time as that annoying period between naps, and limit all non-sleep time as much as possible.
Please move this one up (Score:2)
And if that's not really revelant, the folks from NYC would gain insight into how to finally kick the rat problem.
BAHAHAHA (Score:2)
PH34R!
hell yeah (Score:3)
#----------------------------
$mrp=~s/mrp/elite god/g;
Re:Slashdot Moderation (OT) (proper formatting!) (Score:3)
I think it works pretty well for what it's supposed to do. The problem is a) the nature of the site being general tech news; and b) the quantity of users. We can either a) give all users random moderation points; or b) give a limited group of users moderation points based on criterion such as being moderated up themselves; or c) a mix of both. I think this is best theoretically if tweaked properly.
However, some problems exist such as a) the default linear setup combined with the fact that this is just a news site means lots of good comments at the end of the forum get lost; b) not enough people meta-moderate; c) people mark down comments that they do not necessarily agree with but may be valid points of view, or comments that are slightly off topic but are good extensions of the current conversation; d) people given moderation points often just want to get rid of them. This is a news site after all, and responsibility to the integrity of moderation isn't exactly a priority. Many people just scroll down a bit and moderate comments that vaguely look good. Why? Again, probably because this is just a news discussion site and expending the effort to read all the comments in a story would take many, many hours.
So, I agree with you that it might be good to increase the moderation points available. However, this must be done in a manner that will give points to those who deserve them and not to those who will moderate posts down just because they do not agree with a point or those who will just moderate because at first glance the post looks good.
In short, not enough people meta-moderate so at a macro level, increasing the amount of moderation points to everyone would be bad. It would be a bit better only increasing the amount to those who are consistently moderated up but that does not guarantee that those who moderated them up properly looked at their posts. So we either give a select group a lot of points and allow them to moderate - or we give the group at large a lot of points and hope that they use them wisely. Not enough people meta moderate so this is why such a system can seem broken. The bottom line? It's a discussion news site. Expending the effort is just too much in this situation.
Even then, meta moderation does not give you the thread. This creates a problem because the moderation might be relevant to the post and thread that it replies to. The solution? Tell everyone to quote every time what they are responding to. This is done most of the time, so this is not too much of a major problem.
There is also another improvement that I want. Randomly displayed threads. There are some very good comments that get lost in the noise because we only have an option for newest and oldest in threads or by themselves. This isn't a problem for the 100 comment stories but becomes a large problem for 250+ comment stories. The first problem with randomly displayed nested and threaded comments that comes to mind is that the flow of the discussion often comes linearly, even if not the same thread. However, I think it would be welcome to most slashdot readers. Anyway, to tie this into the moderation problems, it would probably have to be the default setting for proper moderation to occur. Either that or a the owners of the site generating a lot of noise about it.
Wading through so much information and finding signal in noise isn't much fun. I usually just ignore moderation and scroll a lot.
WOW-The Dept. of Veteran's Affairs was involved (Score:3)
The things I've seen at the VA Medical Center East Orange NJ, it wouldn't suprise me!
Post wrong? (Score:5)
Although subjects' memory performance was less efficient with sleep deprivation, greater activity in the parietal region was associated with better memory.
My interpretation of that line is that, overall, students had WORSE memory performance when sleep-deprived, but those students who had greater activity in the parietal region performed better than those with lower activity -- but still worse than they would have had with a good night's sleep. Am I correct in my reading?
Sleep Deprivation can also kill. (Score:5)