Scientists Reverse Aging In Human Cell Lines 24

Posted by samzenpus
from the not-that-old dept.
Eloking writes: Professor Jun-Ichi Hayashi from the University of Tsukuba in Japan has discovered the regulation of two genes involved with the production of glycine are partly responsible for some of the characteristics of aging. With this finding he has been able to "flip the switches on a few genes back to their youthful position, effectively reversing the aging process." The Professor's findings cast doubt on the mitochondrial theory of aging, which proposes that the accumulation of mutations in the mitochondrial DNA are responsible for aging.

Thanks To the Montreal Protocol, We Avoided Severe Ozone Depletion 45

Posted by samzenpus
from the keeping-away-the-UVs dept.
hypnosec writes: Scientists say the ozone layer is in good shape thanks to the Montreal Protocol, which has helped us avoid severe ozone depletion. Research suggests that the Antarctic ozone hole would have been 40% bigger by now if not for the international treaty. "Our research confirms the importance of the Montreal Protocol and shows that we have already had real benefits. We knew that it would save us from large ozone loss 'in the future', but in fact we are already past the point when things would have become noticeably worse," lead author Professor Martyn Chipperfield, from the School of Earth & Environment at the University of Leeds, said in a press release.

A Ph.D Thesis Defense Delayed By Injustice 77 Years 106

Posted by samzenpus
from the better-late-than-never dept.
Taco Cowboy writes: A story about a 102-year old lady doing her PhD thesis defense is not that common, but when the thesis defense was delayed by a whopping 77 years, that gotta raise some eyebrows. Ingeborg Syllm-Rapoport studied diphtheria at the University of Hamburg in Germany and in 1938, the 25-year old Protestant-raised, German-born Ingeborg submitted for her doctorate thesis defense. She was denied her chance for her defense because her mother was of the Jewish ancestry, making her an official "cross-breed". As such the Nazi regime forbid the university from proceeding with her defense, for "racial reasons".

She became one of the thousands of scholars and researchers banished from German academe, which at the time included many of the world's most prestigious research institutions, because of Jewish ancestry or opposition to Nazi policies. Many of them ended up suffering or dying in concentration camps. Rudolf Degkwitz, Syllm's professor, was imprisoned for objecting to euthanizing children. Syllm, however, was able to reach the United States and earned her medical degree from the old Women's Medical College of Pennsylvania in Philadelphia. Eventually she married a fellow physician named Samuel Mitja Rapoport, had a family, and moved back to Germany in the 1950s, where she achieved prominence in neonatology. Syllm-Rapoport, who is now 102 years old, might have remained just a doctor (if a very accomplished one) had not the present dean of the Hamburg medical school, Uwe Koch-Gromus, heard her story from a colleague of her son, Tom Rapoport, a Harvard cell biologist.

Determined to do what he could to mitigate this wrong, Koch-Gromus arranged Syllm-Rapoport's long-delayed defense. Despite failing eyesight, she brushed up on decades of developments in diphtheria research with the help of friends and the Internet. Koch-Gromus called the 45-minute oral exam given by him and two colleagues on 13 May in her Berlin living room "a very good test. Frau Rapoport has gathered notable knowledge about what's happened since then. Particularly given her age, she was brilliant."

Prospects and Limits For the LHC's Capabilities To Test String Theory 123

Posted by samzenpus
from the proving-it-maybe dept.
StartsWithABang writes: The Large Hadron Collider has just been upgraded, and is now making the highest energy collisions of any human-made machine ever. But even at 13 TeV, what are the prospects for testing String Theory, considering that the string energy scale should be up at around 10^19 GeV or so? Surprisingly, there are a number of phenomenological consequences that should emerge, and looking at what we've seen so far, they may disfavor String Theory after all.

SpaceX Cleared For US Military Launches 59

Posted by Soulskill
from the low-earth-orbit-needs-more-lasers dept.
An anonymous reader writes: The U.S. Air Force has given private rocket company SpaceX clearance to launch military satellites into orbit. This disrupts the lock that Boeing and Lockheed Martin have had on military launches for almost a decade. SpaceX will get its first opportunity to bid for such launches in June, when the Air Force posts a contract to launch GPS satellites.

How To Die On Mars 256

Posted by Soulskill
from the get-your-coffin-to-mars dept.
An anonymous reader writes: Many space-related projects are currently focusing on Mars. SpaceX wants to build a colony there, NASA is looking into base design, and Mars One is supposedly picking astronauts for a mission. Because of this, we've been reading a lot about how we could live on Mars. An article at Popular Science reminds us of all the easy ways to die there. "Barring any complications with the spacecraft's hardware or any unintended run-ins with space debris, there's still a big killer lurking out in space that can't be easily avoided: radiation. ... [And] with so little atmosphere surrounding Mars, gently landing a large amount of weight on the planet will be tough. Heavy objects will pick up too much speed during the descent, making for one deep impact. ... Mars One's plan is to grow crops indoors under artificial lighting. According to the project's website, 80 square meters of space will be dedicated to plant growth within the habitat; the vegetation will be sustained using suspected water in Mars' soil, as well as carbon dioxide produced by the initial four-member crew. However, analysis conducted by MIT researchers last year (PDF) shows that those numbers just don't add up."

Creationists Manipulating Search Results 400

Posted by Soulskill
from the pi-is-exactly-3 dept.
reallocate writes: It looks like some Creationists are manipulating search results to ensure websites pushing religion are appearing in response to queries about science. Ask Google "What happened to the dinosaurs?" and you'll see links to Creationist sites right at the top. (And, right now, several hits to sites taking note of it.) Google has a feedback link waiting for you to use it.

Russian Space Agency Misused $1.8 Billion, May Be Replaced 87

Posted by Soulskill
from the that's-a-lot-of-vodka dept.
An anonymous reader writes: After a pair of high profile launch failures in the past few months, Russian space agency Roscosmos is making headlines again: this time for corruption. A public spending watchdog reported that the organization had misused 92 billion rubles ($1.8 billion) in 2014 alone. Deputy Prime Minister Dmitry Rogozin said their space efforts have been undermined by rampant corruption. "We have uncovered acts of fraud, abuse of authority (and) document forgery. With such a level of moral decay, one should not be surprised at the high accident rate." He also said Roscosmos is to be "abolished," and replaced by a state corporation of the same name by the end of the year. "In its new, corporate identity, Roscosmos will be responsible not only for setting mission goals but managing wages for space industry workers and modernizing production facilities."

Can Bad Scientific Practice Be Fixed? 379

Posted by samzenpus
from the what's-in-it-for-me? dept. writes: Richard Horton writes that a recent symposium on the reproducibility and reliability of biomedical research discussed one of the most sensitive issues in science today: the idea that something has gone fundamentally wrong with science (PDF), one of our greatest human creations. The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue. Afflicted by studies with small sample sizes, tiny effects, invalid exploratory analyses, and flagrant conflicts of interest, together with an obsession for pursuing fashionable trends of dubious importance, science has taken a turn towards darkness. According to Horton, editor-in-chief of The Lancet, a United Kingdom-based medical journal, the apparent endemicity of bad research behavior is alarming. In their quest for telling a compelling story, scientists too often sculpt data to fit their preferred theory of the world or retrofit hypotheses to fit their data.

Can bad scientific practices be fixed? Part of the problem is that no-one is incentivized to be right. Instead, scientists are incentivized to be productive and innovative. Tony Weidberg says that the particle physics community now invests great effort into intensive checking and rechecking of data prior to publication following several high-profile errors. By filtering results through independent working groups, physicists are encouraged to criticize. Good criticism is rewarded. The goal is a reliable result, and the incentives for scientists are aligned around this goal. "The good news is that science is beginning to take some of its worst failings very seriously," says Horton. "The bad news is that nobody is ready to take the first step to clean up the system."

Bats' White-Nose Syndrome May Be Cured 88

Posted by samzenpus
from the wipe-your-nose dept.
New submitter alabamatoy writes: Several news outlets are reporting that a common bacteria may be proving successful in curing "white-nose syndrome" which has been decimating the bat populations across North America. A new treatment using a common bacterium was developed in Missouri by Forest Service scientists Sybill Amelon and Dan Lindner, and Chris Cornelison of Georgia State University. The Nature Conservancy reports: "On May 20, 2015, Scientists and conservationists gathered outside the historic Mark Twain Cave Complex in Hannibal, Missouri, to release back into the wild some of the first bats successfully treated for deadly White-Nose Syndrome." Bats are a key player in the environment, keeping insect populations under control, especially mosquitoes.

Sex-Switched Mosquitoes May Help In Fight Against Diseases 148

Posted by samzenpus
from the no-girls-allowed dept.
cstacy writes: Only the female mosquitoes bite and transmit viral diseases such as Dengue Fever. Scientists have finally discovered the elusive genetic switch called Nix, that determines the sex of these blood sucking insects, and hope to selectively eliminate females to control the spread of diseases. "Nix provides us with exciting opportunities to harness mosquito sex in the fight against infectious diseases because maleness is the ultimate disease-refractory trait," explained Zhijian Jake Tu, an affiliate of the Fralin Life Science Institute and a biochemistry professor from Virginia Tech's College of Agriculture and Life Sciences.

Largest Eruption In the Known Universe Is ~100 Times the Size of Milky Way 72

Posted by samzenpus
from the big-boom dept.
StartsWithABang writes: At the center of almost every galaxy is a supermassive black hole (SMBH); at the center of almost every cluster is a supermassive galaxy with some of the largest SMBHs in the Universe. And every once in a while, a galactocentric black hole will become active, emitting tremendous amounts of radiation out into the Universe as it devours matter. This radiation can cut across the spectrum, from the X-ray down to the radio. At the heart of MS 0735.6+7421, there's a >10^10 solar mass black hole that appears to have been active for hundreds of millions of years, something unheard of!

EU Drops Plans For Safer Pesticides After Pressure From US 154

Posted by Soulskill
from the say-it-don't-spray-it dept.
An anonymous reader writes: The European Union recently published plans to ban 31 pesticides containing chemicals linked to testicular cancer and male infertility. Those potential regulations have now been dropped after a U.S. business delegation said they would adversely affect trade negotiations for the Transatlantic Trade and Investment Partnership. "Just weeks before the regulations were dropped there had been a barrage of lobbying from big European firms such as Dupont, Bayer and BASF over EDCs. The chemical industry association Cefic warned that the endocrines issue 'could become an issue that impairs the forthcoming EU-US trade negotiations.'"

Hubble Discovers a Fast-Aging Star Nicknamed "Nasty 1" 29

Posted by samzenpus
from the vanity-plate-ideas dept.
An anonymous reader writes: Using NASA's Hubble Space Telescope, Astronomers have uncovered surprising new clues about a large, rapidly aging star whose behavior has never been seen before. The star is so strange in fact that astronomers have nicknamed it "Nasty 1," a play on its catalog name of NaSt1. Wolf-Rayet stars like NaSt1 are typically large, rapidly evolving stellar bodies that form by shedding their hydrogen-filled outer layers quickly, exposing a bright hot, helium-burning core. Nasty 1 is unique because it contains a disk like structure. "We were excited to see this disk-like structure because it may be evidence for a Wolf-Rayet star forming from a binary interaction," said Jon Mauerhan of UC Berkeley, lead author on the new Nasty 1 paper. "There are very few examples in the galaxy of this process in action because this phase is short-lived, perhaps lasting only a hundred thousand years, while the timescale over which a resulting disk is visible could be only ten thousand years or less."

Machine That "Uncooks Eggs" Used To Improve Cancer Treatment 39

Posted by samzenpus
from the closer-to-a-cure dept.
hypnosec writes: An Australian invention that gained attention for being able to "unboil" an egg has now been put to use in the treatment of cancer. The device has boosted the potency of a common cancer treatment drug, carboplatino, as much as four-and-a-half-times. reports: "Flinders Centre for Innovation in Cancer director Professor Ross McKinnon said it meant a huge advance for cancer treatment. 'It gives us the promise of offering an alternative where we have more drug being delivered to the tumour and less drug being delivered to the rest of the body,' he said. 'That means less side-effects for the patient and hopefully a much better effect in terms of tumour response. What this group are doing is an example of one drug but we would hope we could extend this to many drugs.' The device can process proteins more efficiently than current methods, with possible big ramifications for the pharmaceuticals industry.